HOW DID OPRA LOSE WEIGHT

Checked on January 19, 2026
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Executive summary

Oprah Winfrey’s recent weight loss is the product of a multi-year, multipronged approach: prescribed GLP‑1 class medication, renewed physical activity (notably hiking and strength training after knee surgery), and dietary and lifestyle habits she calls maintenance tools — a combination she has discussed in interviews and in her book Enough [1] [2] [3]. Reporting shows she credits medication with calming appetite and supporting sustainable choices while pairing it with exercise, altered meal timing and hydration habits; she has not publicly named a specific drug [4] [5] [6].

1. The medical pivot: GLP‑1 medications as a core tool

Oprah has said that, after resisting, she began taking a GLP‑1 weight‑loss medication in 2023 and described it as “a relief,” crediting it with helping curb cravings and reshape her relationship with food — language echoed across People, Today and other outlets that reported her experience with the drug class [1] [2] [4]. Multiple profiles and her new book, coauthored with endocrinologist Dr. Ania Jastreboff, frame these drugs as scientifically supported treatments for obesity and for reshaping brain signals tied to appetite, but Oprah and the coverage consistently note she has not publicly disclosed the specific brand or molecule [3] [4].

2. Exercise, surgery and rebuilding physical capacity

The catalyst for a sustained fitness routine was knee surgery in 2021 that allowed Oprah to reintroduce regular movement; she reports progressing from physical therapy to high‑mileage hikes and strength training, which she now cites as daily anchors that complement medication rather than replace it [1] [7] [5]. Outlets summarize her regimen as hiking several miles most days, lifting weights and emphasizing energy and strength gains — framing exercise as part of a holistic maintenance plan rather than the sole driver of her weight loss [7] [5].

3. Nutrition and daily habits: structure, hydration and meal timing

Beyond drugs and motion, Oprah has described concrete habits — eating a final meal earlier in the day, prioritizing hydration and making food choices easier — strategies featured in interviews and expert Q&As that present lifestyle tweaks as necessary supports for long‑term weight management [5] [8]. Coverage also stresses that she treats medication as a maintenance tool within a broader approach that includes those habits, and that the goal she emphasizes is strength and freedom from shame as much as a number on the scale [2] [8].

4. Public context, past programs and commercial ties

Oprah’s weight story is decades old: she previously credited WeightWatchers (WW) and invested in the company, attributing earlier losses to their program, and later resigned from the WW board after publicly saying she’d started a GLP‑1 — a move framed as avoiding conflict of interest while shifting to medication‑assisted management [1] [6]. Critics caution that her evolving public posture still carries commercial and cultural weight: some commentators argue her platform has historically promoted diet culture and that celebrity endorsements can both destigmatize treatment and inadvertently glamorize weight loss as a universal good [9].

5. Limits of available reporting and contested claims

Reporting converges on three certainties — Oprah used GLP‑1 medication, increased exercise after knee surgery, and adopted new daily habits — but gaps remain: she has not named the exact drug in most public accounts, dosage and medical supervision details are private, and long‑term outcomes beyond her personal testimony are still emerging in the press [4] [6] [3]. Voices across People, CBS, Today, Fox and critical outlets like Allure provide both endorsement and scrutiny: advocates highlight relief and medical legitimacy, while critics warn about diet‑culture implications and the celebrity influence on public perception [10] [9] [11].

Want to dive deeper?
Which GLP‑1 medications are approved for weight loss and how do they work?
What does the medical literature say about long‑term outcomes and side effects of GLP‑1 weight‑loss drugs?
How has celebrity discussion of GLP‑1s affected public demand and access to these medications?