Fact check: Was trifft nicht zu Meldung von UAWs zu? Laut Berufsordnung muss Meldung z.B. an AkdÄ erfolgen (Verpflichtung!) Bei Verdacht müssen chronologische und pharmakologische Faktoren berücksichtigt werden  Arzneimittel Interaktionen sind immer als UAW zu bewerten und zu melden  UAW sind nicht erwünschte Wirkungen schwerwiegender Art, die mit der Einnahme von Pharmaka korrelieren Von selten 0.01% bis 10% sehr häufig 

1. Summary of the results

1. Summary of the results:

Based on the provided analyses, the incorrect statement is "Arzneimittel Interaktionen sind immer als UAW zu bewerten und zu melden" (Drug interactions must always be evaluated and reported as ADRs). The analyses show that while adverse drug reactions must be reported, not all drug interactions automatically qualify as reportable ADRs. The reporting obligation to AkdÄ is confirmed, and the consideration of chronological and pharmacological factors is supported by pharmacovigilance practices.

2. Missing context/alternative viewpoints:

• The analyses don't specify the exact criteria for what constitutes a reportable drug interaction versus a normal interaction
• The frequency ranges (0.01% to 10%) mentioned in the original statement aren't verified in any of the analyses
• The role of different reporting bodies (like EudraVigilance database and Paul-Ehrlich-Institut) isn't mentioned in the original statement
• The statement doesn't address the importance of healthcare professionals' judgment in determining what constitutes a reportable ADR

3. Potential misinformation/bias in the original statement:

• The statement oversimplifies the complex nature of drug interactions by suggesting all interactions must be reported
• It presents frequency ranges without proper context or source citation
• It implies that ADRs are only "schwerwiegender Art" (serious nature), while pharmacovigilance systems actually track various severity levels
• The statement doesn't acknowledge the role of professional judgment in determining what constitutes a reportable ADR, potentially misleading healthcare providers into over-reporting or under-reporting incidents