How many active and inactive ingredients are in the Pfizer-BioNTech COVID-19 vaccine (Comirnaty) and what are they?

1. What the public sources here do say about Comirnaty — regulatory status and formulation focus

Pfizer and public health agencies in these search results emphasize that Comirnaty continues to be updated to match circulating SARS‑CoV‑2 sublineages — for example the 2025–2026 LP.8.1‑adapted formulation cited by Pfizer — and that shipping and approvals for age groups have been publicly announced ^{[2] [4]}. The CDC pages in the dataset reference that Comirnaty is one of the 2025–2026 COVID‑19 vaccine options and discuss who it’s recommended for, but the CDC snippets shown do not include ingredient lists ^{[1] [5]}.

2. What these sources do not provide — no ingredient list or counts in the results

None of the provided excerpts include the vaccine’s active ingredient name (e.g., the specific mRNA construct designation) or a full list of excipients/inactive ingredients; the Pfizer press releases and CDC guidance in this set focus on efficacy, approvals, and target strains rather than product‑label ingredient tables ^{[2] [4] [1]}. Therefore, a precise count of “active” vs. “inactive” ingredients and a verbatim list are not present in the current reporting (not found in current reporting).

3. Typical context — what “active” and “inactive” mean and why readers ask this

Search results in this set include background on the difference between active and inactive ingredients in drug products: an inactive ingredient is any component other than the active ingredient and is included for formulation, stability, or manufacturing reasons; regulatory databases record inactive ingredient fields (FDA SRS context referenced here) ^[6]. Consumer resources explain inactive/excipient roles such as stabilizers, preservatives, or vehicles — which is why people often want to see full lists to check allergies or sensitivities ^{[7] [8]}.

4. Where an authoritative ingredient list normally appears (and why it matters)

Authoritative ingredient lists for approved vaccines are typically published in product prescribing information (the FDA label), manufacturer fact sheets, or national immunization program monographs — those sources list the active ingredient and excipients and sometimes quantities. The search results include Pfizer press material and CDC guidance but the particular snippets returned here omit the ingredient table one would expect in a full product label ^{[2] [4] [1]}. The FDA’s inactive ingredient database and field descriptions demonstrate that regulators track excipients and maximum amounts in approved products ^[6].

5. Conflicting or sensational reporting in the dataset — exercise caution

Some media pieces in this result set report on possible adverse findings tied to Pfizer’s vaccine (e.g., a Daily Mail article about eye changes), but these are news reports rather than official ingredient or labeling documents; they do not supply or dispute ingredient lists ^[3]. Readers should separate safety signal reporting from the technical ingredient disclosure — neither the safety article nor the press releases in this set supply the full ingredient list for verification ^{[3] [2]}.

6. How to get the definitive answer and what I can’t assert from these sources

To obtain a verified count and the exact names of active and inactive ingredients, consult the FDA‑approved prescribing information / product label or the manufacturer’s full fact sheet — neither of which appear in the provided snippets. Because the current search results do not include the label or an ingredients table, I cannot state the number or list of ingredients from these sources (not found in current reporting; ^[9]2).

If you want, I can: (a) re-run a targeted search in the dataset for FDA prescribing information, the vaccine fact sheet, or the FDA label for Comirnaty; or (b) summarize a typical mRNA vaccine ingredient profile from external authoritative labels if you provide permission to use sources beyond this set.