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Deaths caused by mrna vaccines

Checked on November 4, 2025
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"deaths caused by mRNA vaccines"
"mRNA COVID vaccine fatalities data VAERS"
"studies on mRNA vaccine mortality risk"
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Executive Summary

The raw counts of deaths reported after mRNA COVID-19 vaccination do not establish that vaccines caused those deaths; federal surveillance and multiple peer-reviewed studies find no consistent signal of increased all-cause mortality attributable to mRNA vaccines, while limited evidence points to rare, specific risks such as myocarditis. Conflicting analyses exist — a 2025 Florida preprint reported higher 12‑month mortality after Pfizer versus Moderna, but that finding is not peer‑reviewed and stands alongside multiple studies and expert reviews that found no increased non‑COVID mortality or deemed evidence for sudden death inconclusive [1] [2] [3] [4] [5] [6].

1. Why big VAERS numbers get attention — and why they don’t prove causation

VAERS lists tens of thousands of deaths reported after COVID‑19 vaccination, and this raw count is often invoked as evidence that mRNA vaccines kill people [1]. VAERS is a passive, open reporting system designed to capture temporal associations, not to adjudicate cause; entries include deaths that occur coincidentally after vaccination, especially in older populations with high baseline mortality. Analytical work and public health agencies caution that VAERS signals require follow‑up with controlled studies and record review to distinguish background mortality from vaccine‑related deaths. Emphasizing raw counts without age‑standardization, denominator data, or clinical review inflates perceived risk and can mislead public health interpretation [1].

2. A head‑to‑head Florida preprint raised alarms — but it remains an outlier and unreviewed

A 2025 preprint reported higher 12‑month all‑cause, cardiovascular, and non‑COVID mortality among Florida adults initially receiving Pfizer‑BioNTech compared with Moderna, suggesting a troubling differential between the two mRNA platforms [2]. That study is a preprint and not peer‑reviewed, and the authors’ design, confounding control, and generalizability require independent validation. Other population‑based designs — including self‑controlled case series and cohort analyses — found no increased risk of all‑cause or cardiac mortality after vaccination and in some instances observed lower mortality among vaccinees, findings that directly contradict a clear causal interpretation of the Florida result [4] [5]. The tension between the preprint and larger surveillance studies highlights the need for reproducible, adjusted analyses.

3. Independent expert reviews say the evidence for sudden death is inadequate or mixed

A National Academies (NASEM) review examined literature on sudden death and COVID‑19 vaccines and concluded that evidence was insufficient to accept or reject a causal link, citing sparse, low‑quality, and methodologically limited studies [3]. This formal conclusion signals that, after multiple investigations, no high‑quality, consistent body of evidence attributes sudden deaths to mRNA vaccines at the population level. The NASEM finding also underscores that absence of definitive proof can reflect limitations in study design, rare event frequency, and reporting completeness rather than proof of safety or harm, so continued rigorous surveillance and transparent data sharing remain essential [3].

4. Known causal risks are narrow, rare, and demographic‑specific

The CDC’s vaccine safety monitoring identifies myocarditis as a causal adverse event associated with mRNA vaccines, particularly in adolescents and young adult males, but emphasizes that cases are rare and most patients recover [6]. This demonstrates that while broad claims that “mRNA vaccines cause deaths” overgeneralize, there are specific, documented vaccine‑associated harms that registries and studies have characterized. Public communication must therefore balance acknowledging rare, real risks with contextualizing them against benefits in preventing COVID‑19 morbidity and mortality, and ensuring clinicians and recipients know how to recognize and manage those adverse events [6].

5. What researchers, clinicians, and the public should watch next

Resolving discrepancies requires replication using robust, adjusted cohort designs, active surveillance, and clinical record review to adjudicate cause of death and control for confounders such as age, comorbidities, and socio‑demographic differences [2] [4] [5]. Reporting biases, differential healthcare access, and vaccine selection patterns can create apparent signals that evaporate under rigorous study. Stakeholders should prioritize peer review of preprints, transparent sharing of individual‑level data, and continued monitoring for rare outcomes while maintaining clear messaging that VAERS counts alone are not proof of causation [1] [7]. Finally, be alert to potential agendas: some actors amplify raw VAERS counts to erode vaccine confidence, while others may understate rare harms to protect public health campaigns; balanced interpretation requires adherence to rigorous epidemiology and up‑to‑date surveillance findings [1] [2] [3].

Want to dive deeper?
Have mRNA COVID-19 vaccines been proven to cause deaths in peer-reviewed studies?
What did the CDC and WHO report about deaths after mRNA vaccination in 2020 2021 2022?
How reliable is VAERS data for determining deaths caused by mRNA vaccines?
What did autopsy or causality investigations find about deaths temporally linked to Pfizer-BioNTech or Moderna vaccines?
What are known rare fatal adverse events associated with mRNA vaccines (e.g., myocarditis, thrombosis) and their incidence rates?