Which over-the-counter supplements has Dr. Oz recommended specifically for neuropathy and peripheral neuropathy?

Checked on January 12, 2026
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Executive summary

Dr. Mehmet Oz has suggested nonprescription, topical options for neuropathic pain—most prominently capsaicin and, in contexts where he discusses natural pain relief, cannabinoids like CBD—while broader lists of oral supplements (B vitamins, omega‑3/fish oil, curcumin, alpha‑lipoic acid, acetyl‑L‑carnitine) appear in medical and patient resources but are not documented in the provided reporting as Dr. Oz’s specific recommendations [1] [2] [3] [4].

1. What the reporting shows Dr. Oz recommending: topical capsaicin and topical CBD

The clearest, attributable recommendation in the supplied reporting is Dr. Oz’s endorsement of topical capsaicin for pain relief; capsaicin, derived from chili peppers, is noted by an article summarizing Dr. Oz’s approach to chronic pain and is described as effective for neuropathic pain when applied as a topical agent [1]. The same piece frames topical CBD as a part of his “natural pain relief” toolkit by citing animal studies suggesting topical CBD can reduce inflammatory and neuropathic pain—though that source relies on preclinical work rather than randomized human trials [1].

2. Claims of a Dr. Oz “gummy” or marketed product for neuropathy: reported but disputed

User‑generated discussion captured on Mayo Clinic Connect reports advertising that Dr. Oz promoted a gummy claiming rapid reversal of diabetes and healing of neuropathy, and notes a commercial tie to investor Mark Cuban; that thread is skeptical and explicitly calls attention to Dr. Oz’s history of controversial promotions, but the post is a community comment and the site warns readers it is not authoritative medical guidance [5]. The reporting therefore documents public claims and ads associated with Dr. Oz’s name but not verifiable clinical evidence that those products work.

3. What the broader supplement literature recommends (and how it differs from Dr. Oz’s documented advice)

A range of over‑the‑counter oral supplements—B‑vitamins (B1/benfotiamine, B6, B12), omega‑3 fish oil, curcumin, alpha‑lipoic acid, acetyl‑L‑carnitine and others—are repeatedly listed across health outlets as potentially helpful for neuropathy, especially when a deficiency is present or in diabetic neuropathy (Healthline; Foundation for Peripheral Neuropathy; WebMD summaries) [2] [3] [6]. However, the supplied reporting does not attribute these oral supplement recommendations to Dr. Oz himself, and systematic reviews of nutraceuticals emphasize heterogeneous, often limited human trial evidence—cautioning that benefits are inconsistent and more rigorous studies are needed [4] [3].

4. Limits of the available reporting and potential commercial motives to note

The assembled sources show Dr. Oz advocating topical capsaicin and discussing topical CBD in the context of natural pain relief, but there is a gap between those discrete mentions and broader lists of oral OTC supplements found elsewhere; none of the provided sources contains a comprehensive, sourced list of Dr. Oz endorsing B‑vitamins, fish oil, alpha‑lipoic acid or similar oral agents specifically for neuropathy [1] [2] [3]. Community discussions and advertising claims tie Dr. Oz’s brand to commercially marketed “gummies” and highlight possible promotional motives—comments explicitly question the validity and flag investors involved—which should temper reliance on such claims until independent clinical data are available [5].

5. Practical takeaway and alternative viewpoints

The practical reading of the reporting is that Dr. Oz has publicly discussed topical treatments—capsaicin most clearly—and referenced topical CBD as promising in preclinical studies for neuropathic pain, while mainstream clinical and patient resources list multiple oral OTC supplements for neuropathy though these are not shown here to be recommendations from Dr. Oz [1] [2] [3]. Independent reviews stress that evidence for many supplements is mixed and that drug interactions and dosing matter [4], and community skepticism about commercialized products associated with media personalities is well documented in the provided discussion [5].

Want to dive deeper?
What clinical trials support using capsaicin or topical CBD for peripheral neuropathy in humans?
Which over‑the‑counter oral supplements have the strongest randomized controlled trial evidence for diabetic peripheral neuropathy?
What oversight and disclosures exist when media figures endorse health supplements or commercial products?