What therapeutic uses or clinical trials involve gelatide?
Executive summary
"Gelatide" appears in two distinct senses in the provided material: as a commercial weight‑loss supplement brand marketed with claims about activating GLP‑1/GIP and delivering rapid weight loss (commercial sites and reviews) [1] [2] [3] [4], and, separately, as the root word "gelatin" which is widely used therapeutically — in drug delivery, tissue engineering, wound dressings, capsules and some clinical studies [5] [6] [7] [8]. Available sources do not describe any registered clinical trials of the specific branded "Gelatide" product, while numerous peer‑reviewed studies and reviews document gelatin/GelMA (gelatin methacryloyl) uses and early clinical evaluations in drug delivery, embolization microspheres and tissue scaffolds [7] [8] [9].
1. Two different stories: brand marketing versus biomedical gelatin
Search results show “Gelatide” primarily as a marketed dietary supplement claiming to support weight loss through ingredient blends (caffeine, green tea, amino acids, plant extracts) and assertions about activating incretin hormones (GLP‑1/GIP) [1] [2] [3]. Those pages are commercial sales or review sites and make efficacy claims but do not point to peer‑reviewed clinical trials of the branded product [1] [2] [3] [4]. Separately, the broader scientific literature and reviews treat gelatin (and modified forms like GelMA) as a biomaterial used in legitimate therapeutic and clinical‑research contexts — drug delivery systems, tissue engineering scaffolds, microspheres used in embolization, and capsule delivery forms [6] [7] [8] [10].
2. What the branded Gelatide claims — and what evidence is cited on its sites
Gelatide marketing pages claim the formula “activates” GLP‑1 and GIP and combines stimulants, thermogenics and amino acids to promote weight loss and curb appetite [1] [2] [3]. Independent reviews flagged by the search record question the novelty and pricing tactics of Gelatide and note an ordinary ingredient list (green tea, guarana, raspberry ketones, capsicum) rather than unique pharmaceutical agents [4]. The commercial pages do not provide links to peer‑reviewed trials of the branded product in humans in the supplied results [1] [2] [3] [4].
3. Clinical and therapeutic uses of gelatin as a material
Peer‑reviewed and review articles identify multiple therapeutic uses of gelatin: as a hydrogel for wound dressing and drug‑delivery, as microspheres and embolic agents (trisacryl gelatin microspheres), and as a scaffold material in tissue engineering including GelMA composites for cartilage and bone repair [6] [7] [8] [9]. Reviews note that many gelatin‑based drug delivery systems have promising preclinical data but that clinical evaluation is still early — some trials used empty or drug‑loaded gelatin microspheres, and gelatin remains under active investigation for translation [7] [8].
4. Examples of gelatin in clinical studies
Clinical examples in the provided sources include vaginal probiotic delivery using gelatin capsules in a double‑blind randomized safety trial (freeze‑dried lactobacilli in gelatin capsules) [11]. Clinical use also appears in interventional radiology where trisacryl gelatin microspheres are used for uterine artery embolization for fibroids, with comparative studies noted [7]. Polymer‑coated gelatin capsules have been trialed in human volunteers to study gastrointestinal behavior [10]. These show gelatin’s role as a delivery vehicle has reached human research in specific contexts [11] [7] [10].
5. Where claims outstrip the evidence — and why that matters
Commercial Gelatide pages make metabolic and hormonal claims without pointing to clinical trials of that branded formula in the supplied material; independent reviewers warn of aggressive marketing, inflated pricing and common weight‑loss ingredients [1] [2] [4]. By contrast, academic sources document gelatin’s biomedical roles backed by preclinical data and a limited number of clinical evaluations focused on delivery systems and scaffolds [7] [8] [9]. The distinction matters because therapeutic credibility depends on peer‑reviewed clinical evidence for a product or drug — sales pages and unverified reviews are not the same as controlled clinical trials [1] [2] [4] [7].
6. Bottom line and reporting limits
Available sources do not identify any registered clinical trials evaluating the commercial “Gelatide” weight‑loss supplement itself [1] [2] [3] [4]. The literature clearly supports therapeutic and clinical research applications of gelatin and modified gelatin (GelMA) — in drug delivery, embolic agents, implants and tissue engineering — but these are scientific uses of gelatin as a biomaterial, not evidence that the marketed Gelatide supplement is clinically validated [6] [7] [8] [11]. Further verification would require trial identifiers or peer‑reviewed papers explicitly testing the branded product; such documents are not found in the provided results.