How do hormone therapies affect aggression and sex offender behavior in trans women?

1. Summary of the results

The analyses provided suggest that hormone therapies do not have a significant impact on aggression and sex offender behavior in trans women ^[1]. A systematic review found mixed evidence on aggression-related outcomes after gender-affirming hormone therapy, but larger prospective cohorts showed no change in anger intensity ^[1]. Similarly, a prospective ENIGI cohort study found that anger proneness did not change after initiation of hormone therapy in trans women ^[2]. Another study found that testosterone therapy did not increase aggression in trans men nor decrease it in trans women, and that aggression scores were unrelated to serum testosterone/estradiol levels ^[3]. Higher anxiety and lower social support were found to be predictors of higher self-reported aggression, rather than hormone therapy itself ^{[2] [3]}. There is no evidence to suggest that hormone therapy is linked to sex-offender behavior ^{[1] [3]}.

2. Missing context/alternative viewpoints

Some analyses highlight the importance of considering anxiety and social support as factors that can influence aggression in trans women ^{[2] [3]}. Others emphasize the need for gender-affirming care, including hormone therapy, to improve wellbeing in trans individuals ^[4]. However, these sources do not provide empirical findings on the specific impact of hormone therapy on aggression or recidivism in trans women ^[4]. Additionally, some studies focus on barriers to medically supervised hormone therapy and the associated health risks, but do not address the impact of hormone therapy on aggression or sex offender behavior ^[5]. Nonprescribed hormone use is also a concern, particularly among trans women who may face barriers to accessing medically supervised hormone therapy ^[5]. Alternative viewpoints may include considering the complex interplay of public policies, social context, and discrimination that can influence the lives of trans women and their access to healthcare ^[5].

3. Potential misinformation/bias in the original statement

The original statement may be misleading in implying a direct link between hormone therapies and aggression or sex offender behavior in trans women ^{[1] [2] [3]}. This framing may perpetuate harmful stereotypes about trans women and contribute to discrimination and stigma ^[6]. The analyses suggest that anxiety, social support, and access to healthcare are more significant factors influencing aggression and wellbeing in trans women ^{[2] [3]}. By focusing on hormone therapy as a potential cause of aggression or sex offender behavior, the original statement may distract from the real issues facing trans women, such as barriers to healthcare and discrimination ^{[5] [4]}. This framing may benefit those who seek to pathologize or stigmatize trans women, but it does not align with the evidence presented in the analyses ^{[1] [2] [3]}.