Is medical malpractice the 3rd cause of death?

Checked on December 21, 2025
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Executive summary

The assertion that medical malpractice (medical errors) is the third-leading cause of death in the United States stems mainly from a Johns Hopkins analysis estimating ~250,000 deaths annually and placing errors behind only heart disease and cancer [1]; but methodological critics and public‑health experts warn that this figure rests on extrapolations, imperfect death‑certificate coding, and differing definitions of “medical error,” so the claim remains contested rather than an official CDC ranking [2] [3].

1. The study that launched the claim — what it did and what it found

A 2016 Johns Hopkins team reviewed multiple studies and hospital data to estimate that roughly 251,000 U.S. deaths per year are associated with medical error, which the authors and many outlets summarized as “third leading cause of death” after heart disease and cancer [1] [4]; this estimate was widely amplified by news sites, specialty blogs, and law‑firm pages that repeat the 250k number as a headline finding [5] [6].

2. Why many experts say the number is plausible but not definitive

Patient‑safety literature and clinical reviews acknowledge medical errors as a serious public‑health problem and note that some analyses have produced figures in the hundreds of thousands that would put errors among top causes of death, meaning the phenomenon merits urgent system reforms regardless of rank [7] [8]; NPR and Johns Hopkins researchers themselves call attention to undercounting on death certificates and to the need for better surveillance to capture errors’ contribution to mortality [2].

3. The methodological cracks critics emphasize

Skeptics argue the Johns Hopkins-derived number depends on extrapolations from heterogeneous studies, sometimes focusing on Medicare subpopulations or incidents where an error occurred and a death followed — which does not prove causation — and then scaling those rates to the entire U.S. population, a process that inflates uncertainty [3] [9]. McGill’s Office for Science and Society and other critics point out that some source studies sampled older or sicker patients and counted events where errors “contributed” but may not have been the proximate cause of death, challenging the direct causal inference needed to label errors as the third‑leading cause [3].

4. How the figure has been used, misused, and weaponized

The 250k figure’s dramatic nature made it politically and rhetorically useful: it has been cited by advocacy groups, alternative‑medicine proponents, and even the NRA to argue various points about healthcare risks or policy, sometimes in ways that overstate certainty or compare unlike statistics [9]. Trade‑ and law‑firm pages have also recycled the claim to underline malpractice litigation markets, which can create incentives to present an unqualified claim that medical error is the third leading cause [10] [11].

5. What authoritative trackers say and the practical upshot

The Centers for Disease Control and Prevention do not currently list “medical error” as a distinct category on standard death certificates; consequently, there is no official CDC ranking that places errors third, and patient‑safety researchers continue to call for improved coding and surveillance rather than acceptance of a single unambiguous ranking [2] [7]. In short, several high‑quality analyses suggest that preventable medical harm causes a very large number of deaths and could rank among top causes if measured differently, but the specific claim “medical malpractice is the third leading cause of death” is better described as a contested interpretation of imperfect data than settled fact [1] [3].

Conclusion

The most responsible reading of the evidence is dual: medical errors are a major, underrecognized contributor to mortality in the U.S., and some peer‑reviewed estimates place them around the third spot [1] [8], but methodological limitations, coding practices, and disputes over attribution mean the label “third leading cause” remains debated and not an official CDC classification [2] [3]. Policymakers and journalists should emphasize the scale of the patient‑safety problem and press for better data rather than treating the 250,000 number as an uncontested statistic [7] [9].

Want to dive deeper?
How do death certificates and ICD coding affect counting deaths from medical error?
What methodological approaches have researchers proposed to better attribute deaths to medical errors?
How have patient safety reforms changed preventable harm rates in U.S. hospitals since 2016?