Fact check: What is the recommended dosage of ivermectin for humans?

1. Summary of the results

The recommended dosage of ivermectin for humans varies depending on the condition being treated, but a single oral dose of 150-200 µg/kg is commonly cited ^{[1] [2]}. This dosage is typically used to treat onchocerciasis, lymphatic filariasis, and strongyloidiasis ^{[1] [2]}. The FDA-approved dose of ivermectin for human use is 200 µg/kg (0.2 mg/kg), typically given as a single dose ^[2]. However, some studies have explored higher doses, up to 10 times the approved dose, for safety and efficacy ^[3]. It is essential to note that ivermectin is not approved for the treatment or prevention of COVID-19 ^{[4] [5]}, and taking large doses can be dangerous ^[5].

2. Missing context/alternative viewpoints

• The original statement lacks context regarding the specific condition being treated, which is crucial in determining the recommended dosage ^{[1] [2]}.
• Some sources highlight the risks associated with off-label and excessive dosing of ivermectin, particularly in the context of COVID-19 prevention and treatment ^{[6] [7]}.
• The use of ivermectin in mass-drug-administration programs for onchocerciasis and strongyloidiasis is mentioned, but the frequency and duration of treatment are not explicitly stated ^[1].
• Alternative viewpoints on the use of ivermectin for COVID-19 treatment are presented, with some sources discussing its antiviral activity against SARS-CoV-2 in vitro ^[8], while others emphasize the lack of FDA approval for this indication ^{[4] [5]}.

3. Potential misinformation/bias in the original statement

The original statement may be misleading as it does not provide context about the specific condition being treated or the potential risks associated with ivermectin use ^{[6] [7]}. Additionally, the statement may imply that ivermectin is approved for COVID-19 treatment, which is not the case ^{[4] [5]}. Pharmaceutical companies and health organizations may benefit from accurate information about ivermectin dosages and uses, while individuals seeking treatment may be misled by incomplete or inaccurate information ^{[1] [2] [5]}. Researchers and healthcare professionals may also benefit from a thorough understanding of the recommended dosages and potential risks associated with ivermectin use ^{[1] [2]}.