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Fact check: What are the inactive ingredients in human ivermectin tablets?
1. Summary of the results
Based on the analyses provided, human ivermectin tablets contain several standard pharmaceutical inactive ingredients. The most comprehensive information comes from the package insert, which lists the following inactive ingredients: microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, pregelatinized starch, and magnesium stearate [1].
Additional formulation data shows that Stromectol, a commercial ivermectin product, contains microcrystalline cellulose, pregelatinized starch, magnesium stearate, butylated hydroxyanisole, and citric acid anhydrous powder [2]. Research on orally disintegrating tablet formulations mentions excipients including mannitol, croscarmellose, and magnesium stearate [3].
The analyses reveal that magnesium stearate and microcrystalline cellulose appear consistently across different formulations, serving as common pharmaceutical excipients in ivermectin tablets.
2. Missing context/alternative viewpoints
The original question lacks important context about formulation variations between different manufacturers and product types. One analysis notes that there are various excipients available for ivermectin formulations, including anhydrous citric acid, butylated hydroxyanisole, and other cellulose derivatives, but doesn't specify which are used in human tablets [4].
Different pharmaceutical companies may use varying inactive ingredient profiles for their ivermectin tablets, as evidenced by the differences between the standard formulation [1] and the Stromectol formulation [2]. Additionally, specialized formulations like orally disintegrating tablets require different excipients such as superdisintegrants, sweetening agents, and specific diluents [3].
The question also doesn't address whether the person is asking about specific brand formulations versus generic versions, which could have different inactive ingredient profiles while maintaining the same active pharmaceutical ingredient.
3. Potential misinformation/bias in the original statement
The original question itself appears to be a straightforward factual inquiry without apparent bias or misinformation. However, the lack of specification about which particular ivermectin tablet formulation could lead to incomplete or potentially misleading answers, as different manufacturers and formulation types contain varying inactive ingredients.
One analysis was unable to provide relevant information about inactive ingredients [5], which highlights the importance of consulting official pharmaceutical documentation and package inserts rather than general medical literature when seeking specific formulation details.