What migraine medications are covered under Medicare Part D?

Checked on December 7, 2025
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Executive summary

Medicare Part D generally covers prescription migraine medicines you take at home, but exact drugs vary by each Part D plan’s formulary; beneficiaries must check plan formularies or the Medicare Plan Finder to confirm whether a specific migraine drug (for example, oral CGRP preventives like atogepant) is covered and what cost-sharing applies [1] [2]. Starting January 1, 2025, the Inflation Reduction Act caps annual out‑of‑pocket prescription spending for Part D at $2,000, which affects how much you will pay for covered migraine medications [3] [4].

1. What “Part D covers” — the short, practical reality

Medicare Part D is the benefit that “covers most migraine treatments you use at home,” meaning oral preventive and acute prescription drugs filled at a pharmacy are generally handled by Part D plans rather than Original Medicare (Part A/B) [5] [1]. Injection or infusion treatments and clinician‑administered therapies (for example, office Botox for chronic migraine) are typically billed to Part B when given in a medical setting, not to Part D [6]. For any individual, coverage depends on the specific Part D plan’s formulary and rules [2] [7].

2. Formularies decide which migraine drugs are covered

Each Part D plan publishes a formulary — a list of drugs the plan covers — and formularies differ across insurers and plan types [8] [7]. National plans (Cigna, Medica, plan sponsors) update formularies each year and may add/remove drugs or move them between cost tiers; beneficiaries must check the current formulary for the relevant plan year [9] [10]. If a drug is “not on formulary” you can request exceptions, but approval is plan‑specific [7].

3. Examples and cost mechanics beneficiaries must know

Recent reporting highlights that brand‑name preventive oral CGRP agents (for example, atogepant/Qulipta) are FDA‑approved for migraine prevention and appear in Part D plans, but beneficiaries still face coinsurance until they reach their out‑of‑pocket cap — in 2025 plans a common coinsurance stage charges 25% until the $2,000 threshold is reached [11] [4]. The Medicare site explains standard Part D stages — deductible (if any), initial coverage (commonly 25% coinsurance), and out‑of‑pocket accumulation toward the catastrophic threshold — and caps on deductibles (no more than $590 in 2025) [4].

4. Important 2025 policy change that affects migraine drug spending

The Inflation Reduction Act’s implementation for 2025 established an annual out‑of‑pocket cap of $2,000 for Medicare Part D prescription drugs; this materially limits how much someone taking expensive migraine medications may pay in a year, but does not change which drugs are on a plan’s formulary [3] [2]. Plans and patient advocates have flagged this as a lifeline for people with high drug costs, including many living with migraine [3].

5. Where Part B still matters: procedures and office treatments

Clinician‑administered therapies used for migraine — notably on‑label Botox injections for chronic migraine — are generally covered under Part B because they are provided in a medical setting; documentation and coding by the provider are needed for correct Part B claims [6]. Other office‑based drugs may also route through Part B rather than Part D; check with your provider and plan.

6. How to confirm coverage for your specific migraine medicine

Do not assume coverage: use the Medicare Plan Finder or a plan’s current formulary PDF to verify whether a specific migraine drug is covered, what tier it sits in, and whether prior authorization, step therapy, or quantity limits apply [2] [10]. If your drug is not listed, the plan’s exception process is an available avenue [7].

7. Conflicting priorities and what the sources reveal

Plans must balance cost containment and access; formularies are updated annually and may drop or restrict drugs even mid‑year, creating unpredictability for patients [9]. Advocacy organizations present the IRA cap as patient‑focused relief [3] [2]; insurers emphasize formulary management and clinical review [8] [7]. Available sources do not list a single universal list of migraine drugs covered by all Part D plans — coverage is plan‑by‑plan [2].

Limitations: This analysis is based on plan guidance, CMS formulary rules, and consumer/advocacy reporting in the provided sources; it does not substitute for checking your specific plan’s formulary or talking to your clinician and plan representative [9] [2].

Want to dive deeper?
Which triptan and CGRP migraine drugs are commonly covered by Medicare Part D plans?
How do Medicare Part D formularies decide coverage for new migraine biologics like gepants and monoclonal antibodies?
What steps can beneficiaries take if their Medicare Part D plan denies coverage for a prescribed migraine medication?
How do Medicare Part D formularies differ in coverage and out-of-pocket costs for preventive versus acute migraine treatments?
Can Medicare Part D cover off-label or compounded migraine treatments, and how can patients request exceptions?