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New England Journal of Medicine
Executive summary
The New England Journal of Medicine (NEJM) is a weekly, peer‑reviewed general medical journal that publishes original research, review articles, and editorial opinion; its current online site lists recent issues, articles, and “recently published” items including November 2025 content [1] [2]. The NEJM current issue and table of contents for mid–late November 2025 (Vol. 393) are available online, with specific items such as clinical case debates, reviews (e.g., Acromegaly updated Nov 14, 2025), and trials published around Nov 19–21, 2025 [3] [4] [5] [6].
1. What NEJM is and how it presents content
NEJM is produced by NEJM Group, part of the Massachusetts Medical Society, and functions as a weekly general medical journal that publishes new medical research, reviews, opinion pieces, and case‑based features; its homepage and “recently published” pages summarize article types and recent items [1] [2]. The site organizes material by issue (Volume 393 for November 2025) and by article category (Research, Review, Clinical Case, Media, Image Challenge), with issue and index pages listing published items by date and volume [7] [6].
2. What’s in the November 2025 issues highlighted by your search
Search results point to NEJM Vol. 393 issues dated mid– to late‑November 2025 and several specific items: a Clinical Decisions feature “To Treat or Not to Treat? Watchful Waiting or Oral Antihypertensives for Asymptomatic Inpatient Hypertension” published online Nov 19 and in the Nov 20 issue (Vol. 393 No. 20) [3]. Other entries include a November 21, 2025 publication on “Medical Management and Revascularization for Asymptomatic Carotid Stenosis” [5] and an updated Review on Acromegaly (updated Nov 14, 2025) [4]. The NEJM “Current Issue” page and “Recently Published” listings reflect multiple items across Nov 12–21, 2025 [6] [2].
3. Examples of research and media coverage referenced
The NEJM site lists both high‑profile clinical trials and earlier‑stage studies in press materials linked to NEJM publications: for example, press coverage claims Pfizer’s mRNA influenza vaccine phase III results were published in NEJM (a secondary site reporting that claim cites NEJM publication) and IAVI reports a Phase 1 Lassa vaccine study published in NEJM on Nov 6, 2025 [8] [9]. Note: the search results include third‑party press releases and summaries referencing NEJM publications rather than the NEJM pages themselves [8] [9].
4. How to use NEJM pages to verify claims
NEJM’s table of contents and “recently published” sections provide DOI links, article types, publication dates, and author affiliations that let readers confirm primary reporting [3] [2]. For any specific claim (e.g., trial efficacy numbers, safety signals), consult the article DOI page or full text listed on NEJM’s site—those pages present the detailed results, methods, and disclosures [3] [4]. Press releases or news sites citing NEJM should be cross‑checked against the NEJM article itself because secondary accounts may overstate or summarize results [8] [9].
5. Competing perspectives and limitations in this sample of results
The search results show a mix of NEJM primary pages (issue TOC, article DOIs, review updates) and external press summaries that assert NEJM publication of specific trial outcomes [6] [3] [5] [8] [9]. NEJM entries provide authoritative publication details (dates, volume, DOI) while outside press pieces may frame clinical implications more optimistically; readers should treat press summaries as secondary and prefer the NEJM DOI/full‑text for definitive data [2] [3]. Available sources do not mention other queries you might have about NEJM editorial policy or subscription access beyond these listings—those details are not found in current reporting provided here.
6. Practical next steps for a reader seeking more detail
If you want the full data and author disclosures for any of these items, click the DOI links on the NEJM article pages (for example the Clinical Decisions piece has DOI and online publication info for Nov 19–20, 2025) and read the full text or supplementary material [3]. Use the Issue Index and “Recently Published” pages to navigate Vol. 393 and the November 2025 entries [7] [2]. For claims reported in the press (e.g., vaccine efficacy), compare the press release to the NEJM article itself to confirm endpoints, effect sizes, and safety details [8] [9].
7. Bottom line
NEJM’s website is the authoritative place to verify what it has published and when; the search results here document multiple November 2025 NEJM publications (Vol. 393) and a mix of primary NEJM pages and external press items that reference NEJM publications—always read the NEJM DOI/full text for final verification [6] [3] [2].