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Fact check: What did Oprah Winfrey use to lose weight?

Checked on July 29, 2025

1. Summary of the results

Based on the analyses provided, Oprah Winfrey used prescription weight-loss medication as her primary tool for weight management. Specifically, she used a GLP-1 agonist, a type of weight-loss medication similar to Ozempic that helps control cravings [1] [2]. Winfrey has been transparent about using this medication as a "maintenance tool" rather than a quick fix [3].

Her approach was comprehensive and multifaceted, combining the medication with:

  • Regular exercise, particularly hiking [4]
  • Lifestyle modifications, including eating her last meal by 4 p.m. [4]
  • Balanced diet and regular exercise as part of a larger lifestyle change [2]

Winfrey has been vocal about ending the shame surrounding weight-loss medications and has emphasized that obesity is a disease that can benefit from medical intervention, though these medications should be combined with diet and exercise rather than used as standalone solutions [5].

2. Missing context/alternative viewpoints

The original question lacks several important contextual elements:

  • Medical legitimacy: The analyses reveal that Winfrey's approach aligns with medical recommendations that weight-loss medications like Wegovy are not "easy fixes" and require combination with lifestyle changes [5]
  • Public health advocacy: Winfrey used her platform to create a TV special addressing weight loss drugs and obesity, positioning herself as an advocate for treating obesity as a legitimate medical condition rather than a character flaw [5]
  • Anti-fraud stance: Importantly, Winfrey actively warns fans against companies misusing her name and image to sell unauthorized weight-loss products like gummies or diet pills [6]. The FTC has taken legal action against companies using fake celebrity endorsements, including Winfrey's name, to market bogus weight-loss products [7]

3. Potential misinformation/bias in the original statement

The original question itself is neutral and factual, seeking information rather than making claims. However, the context reveals potential areas where misinformation could arise:

  • Fraudulent product associations: Companies have illegally used Winfrey's name and image to promote unauthorized weight-loss products, creating false associations between her success and unrelated supplements [6] [7]
  • Oversimplification risk: Without proper context, people might assume medication alone was responsible for her weight loss, when the evidence shows she used a comprehensive approach combining medical intervention with lifestyle changes [4] [2]
  • Commercial exploitation: The analyses suggest that various companies benefit financially from either legitimately discussing her medically-supervised approach or illegally misappropriating her image to sell unrelated products, demonstrating how celebrity weight-loss stories can be exploited for commercial gain.
Want to dive deeper?
What diet plan did Oprah Winfrey follow for her weight loss journey?
How much weight did Oprah Winfrey lose using Weight Watchers?
What role did exercise play in Oprah Winfrey's weight loss transformation?
Which weight loss products has Oprah Winfrey publicly endorsed?
How has Oprah Winfrey maintained her weight loss over the years?