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Fact check: What is the science behind the weight loss products endorsed by Oprah Winfrey?

Checked on August 19, 2025

1. Summary of the results

The analyses reveal that Oprah Winfrey has not endorsed weight loss gummies or similar products, contrary to what many fraudulent advertisements claim. Instead, Oprah has been transparent about using GLP-1 agonist medications (such as Ozempic) as part of her weight loss journey [1].

The science behind her actual weight loss approach involves:

  • GLP-1 medications that mimic the hormone GLP-1, helping people feel full and slowing stomach emptying [1]
  • These medications work by affecting the brain and reducing what experts call "food noise" - the constant thoughts about food [2]
  • Lifestyle changes including healthy diet and exercise, which Oprah credits alongside the medication [1]
  • Use of the medication as a "maintenance tool" rather than a quick fix [3]

Dr. Ania Jastreboff, a Yale researcher, has worked with Oprah to explain how these medications facilitate weight loss by affecting brain chemistry [4].

2. Missing context/alternative viewpoints

The original question assumes Oprah endorses weight loss products, but critical context is missing:

  • Oprah actively warns against weight loss gummies that falsely claim her endorsement, stating she "has nothing to do with them" and doesn't want people to be taken advantage of [5] [6]
  • Her weight loss success comes from medically supervised GLP-1 medications, not over-the-counter supplements or gummies [1] [2]
  • Oprah emphasizes that obesity is a disease, not just a matter of willpower, challenging traditional weight loss narratives [4]
  • She credits her initial weight loss foundation to lifestyle changes following WW (Weight Watchers) before incorporating medication [5]

Companies selling fraudulent weight loss gummies benefit financially from misusing Oprah's name and image, despite her explicit warnings against such products [6].

3. Potential misinformation/bias in the original statement

The original question contains inherent bias by assuming Oprah endorses weight loss products when she explicitly does not. This assumption:

  • Perpetuates fraudulent marketing schemes that misuse her name and likeness [6] [5]
  • Ignores her actual transparency about using prescription medications under medical supervision [3] [1]
  • Misleads people toward unregulated supplements instead of evidence-based medical treatments [5]

One source [7] appears to be deliberately misleading by claiming Oprah has endorsed specific weight loss gummies, which directly contradicts her public warnings against such products. This type of content benefits supplement companies that profit from false celebrity endorsements while potentially harming consumers who purchase unregulated products instead of seeking proper medical care.

The question should be reframed to ask about the science behind GLP-1 medications that Oprah actually uses, rather than implying she endorses commercial weight loss products.

Want to dive deeper?
What are the ingredients in the weight loss products endorsed by Oprah Winfrey?
Do Oprah Winfrey's weight loss products have any scientific backing from 2022 studies?
How do Oprah Winfrey's weight loss products compare to other celebrity-endorsed weight loss products in 2024?
What are the potential side effects of using Oprah Winfrey's weight loss products as of 2025?
Are Oprah Winfrey's weight loss products approved by the FDA in 2023?