Fact check: What is Oprah Winfrey's favorite weight loss supplement?

1. Summary of the results

Based on the analyses provided, Oprah Winfrey does not have a publicly disclosed "favorite weight loss supplement." Instead, the sources consistently reveal that she uses prescription weight-loss medications, specifically GLP-1 agonist medications ^[1]. These are not supplements but rather prescription drugs that include brand names such as Ozempic, Wegovy, Mounjaro, Trulicity, and Zepbound ^[2].

Winfrey has been open about using these medications as a "maintenance tool" for weight management ^[3] and as part of a holistic approach to maintaining a healthy weight ^[3]. She has specifically worked to reduce the shame and stigma around obesity and has stated she is "absolutely done with the shaming" regarding weight-loss medication use ^{[4] [3]}.

2. Missing context/alternative viewpoints

The original question fundamentally mischaracterizes Winfrey's approach to weight management by asking about "supplements" rather than prescription medications. Several important contextual elements are missing:

• Medical vs. Commercial Distinction: The question implies Winfrey endorses over-the-counter supplements, when she actually uses prescription anti-obesity medications under medical supervision ^[4]
• Educational Advocacy: Winfrey has used her platform to educate the public about weight-loss medications through TV specials and conversations with medical experts like Dr. Ania Jastreboff from Yale ^[2]
• Stigma Reduction Efforts: Her public disclosure serves a broader purpose of reducing shame around obesity treatment rather than promoting specific products ^{[4] [3]}
• Holistic Approach: The sources indicate she views medication as one tool among many in weight management, not as a standalone solution ^[3]

3. Potential misinformation/bias in the original statement

The question contains several problematic assumptions that could perpetuate misinformation:

• Supplement vs. Medication Confusion: By asking about "supplements," the question conflates over-the-counter products with prescription medications, potentially misleading people about the nature of effective weight-loss treatments
• Commercial Endorsement Implication: The phrasing suggests Winfrey has a commercial "favorite" product, when the sources show she discusses prescription medications in an educational context rather than endorsing specific brands ^[1]
• Oversimplification: The question reduces complex medical treatment to a simple product recommendation, ignoring the medical supervision and holistic approach that characterizes responsible weight-loss medication use ^{[5] [3]}

This type of question could benefit those who profit from weight-loss supplement sales by creating confusion between legitimate medical treatments and unregulated commercial products.