What are the typical binders used in oral ivermectin tablets?
Executive summary
Stromectol (ivermectin) 3 mg oral tablets and the generic products list several inactive ingredients on the FDA label — notably microcrystalline cellulose and pregelatinized starch among others — which are the typical binders/fillers cited for this formulation [1]. Generic ivermectin tablets are widely available and contain the same active dose strengths cited by clinical references [2] [3] [4], but specific excipient mixes can vary across manufacturers [5].
1. What the official product label actually lists
The FDA-approved Stromectol tablet description names the inactive ingredients found in the 3-mg tablet: microcrystalline cellulose, pregelatinized starch, magnesium stearate, butylated hydroxyanisole (BHA), and citric acid powder, alongside the active ivermectin substance [1]. That list is the primary authoritative source for the composition of that branded oral tablet and establishes which excipients are “typical” for the commercial formulation described in the label [1].
2. Which of those ingredients are usually called “binders” in practice
Among the excipients named on the label, microcrystalline cellulose and pregelatinized starch are the two most commonly cited as binders or filler/disintegrant-type excipients in solid oral dosage forms in standard pharmaceutical formulations; they appear on the Stromectol ingredient list and thus represent the tablet’s main non-active structural components [1]. The FDA label provides the ingredient names but does not catalogue each excipient’s functional role within the tablet in the excerpts provided [1].
3. Other listed excipients and their presence in the tablet
Magnesium stearate, listed on the label, is present in the tablet; the FDA label calls it an inactive ingredient alongside BHA and citric acid powder, confirming their inclusion in the commercial product [1]. The prescribing and drug-information sources reiterate the tablet strengths and commercial availability of 3-mg tablets, reinforcing that these inert ingredients accompany the active ivermectin in standard preparations [2] [3] [4].
4. Variation across manufacturers and generics
Ivermectin is available as both a branded product (Stromectol) and generic tablets; clinical guides and drug information note generic availability and standard dosing strengths, which implies that while the branded label lists specific excipients, generics may use equivalent but not identical excipient blends [5] [6]. The public clinical resources provided do not supply a comprehensive cross-manufacturer excipient comparison, so exact binder composition can vary by manufacturer and country [5].
5. Limits of the reporting and what remains unconfirmed here
The sources at hand clearly document the ingredient list for Stromectol and confirm common tablet strengths and dosing [1] [2] [3], but they do not provide a detailed, source-cited mapping of each excipient to its functional role within the ivermectin tablet in these excerpts. Therefore, while microcrystalline cellulose and pregelatinized starch are listed and are the typical candidates termed “binders” on the label, the provided material does not explicitly define the manufacturers’ stated functional assignment for each inactive ingredient [1].
6. Practical takeaway for clinicians, pharmacists and patients
For those needing to know which binders are “typical” in the marketed ivermectin tablet, the FDA Stromectol description names microcrystalline cellulose and pregelatinized starch among the inactive ingredients, with magnesium stearate, BHA and citric acid also present in the formulation [1]; standard drug references and patient information corroborate the tablet strengths and commercial forms in which these ingredients appear [2] [3] [4]. To confirm the precise excipient roles or to check for allergens or other formulation differences, pharmacists and prescribers should consult the specific product’s full prescribing information or the generic manufacturer’s specifications, which can vary and are not exhaustively detailed in the sources provided here [1] [5].