What percentage of phytonutrients in milk does pasteurization eliminates?

Checked on November 29, 2025
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Executive summary

Pasteurization reduces some heat-sensitive vitamins in milk—studies find measurable decreases in B1 (thiamine), B2 (riboflavin), vitamin C and folate, while effects on B6 are not statistically significant; authors conclude overall nutritive losses are small because many of these vitamins are present at low levels in milk to begin with [1]. Reviews of bovine and donor human milk find “minimal to no impact” on major macronutrients and many vitamins but acknowledge moderate-to-extensive loss of some heat-sensitive bioactive proteins depending on method and temperature [2] [3] [4].

1. What the systematic reviews actually measured — vitamins fall, minerals stay

Meta-analyses of pasteurization studies report statistically significant decreases in vitamin B1 (SMD –1.77), B2 (SMD –0.41), vitamin C (SMD –2.13) and folate (SMD –11.99), while vitamin B6 showed no significant change (SMD –2.66; P = 0.06) [1]. Multiple reviews emphasize that minerals such as calcium and phosphorus are largely unaffected by heat treatments used for pasteurization [5] [6].

2. “What percentage” is hard to state from available reviews

The sources provided report standardized mean differences and note statistically significant declines for several vitamins but do not supply a single, clear percentage of “phytonutrients” lost across milk [1] [7]. Available sources do not mention a consolidated percentage figure for all phytonutrients eliminated by pasteurization; individual studies report different magnitudes depending on temperature, time, and analytic method [4].

3. Phytonutrients vs. vitamins vs. bioactive factors — semantics matter

Most scientific reviews distinguish vitamins and bioactive proteins from “phytonutrients” (plant-derived compounds). Milk is an animal product and contains vitamins, minerals, enzymes, immunoglobulins and other bioactive factors rather than plant phytonutrients; the literature you provided evaluates vitamins and proteins rather than plant phytonutrients per se [1] [4]. If by “phytonutrients” you mean heat-sensitive bioactive factors (e.g., antimicrobial proteins), reviews show moderate to extensive losses for some of these after Holder pasteurization (62.5 °C for 30 min) in donor human milk [3] [4].

4. Pasteurization method and starting material change the outcome

Heat-time combinations matter: high-temperature short-time (HTST, ~72 °C for 15 s) used for commercial bovine milk differs from Holder pasteurization (62.5 °C for 30 min) used in milk banks. Modern pasteurizers and shorter exposure times tend to preserve more heat-sensitive components than older, longer treatments; reviews stress variability across methods and decades of data [2] [4].

5. Nutritional significance vs. analytical significance

Authors underscore a key point: decreases in some vitamins are measurable, but may be nutritionally small because the affected vitamins are present at low concentrations in milk and because other public-health measures (e.g., fortification of commercial milk with vitamin D) offset losses [1] [8]. Public-health authorities emphasize that pasteurization’s disease-prevention benefits greatly outweigh modest changes in certain nutrients [9] [10].

6. Competing narratives — safety and public-health versus “raw milk” advocacy

Scientific reviews explicitly counter pro‑raw‑milk claims that pasteurization “destroys important vitamins” and argue that pasteurization’s safety gains are well established [1] [9]. Advocacy sites and antigovernment or nostalgia-driven outlets claim more severe nutritional harm; those sources are present in the dataset but are not supported by the systematic reviews cited here, which report modest nutrient changes and stress methodological limits in older studies [11] [7].

7. What the evidence does not say (limitations you should note)

Current reporting in these sources does not provide a single percentage that quantifies “phytonutrients” eliminated across all forms of milk by all pasteurization methods; numerical results vary by nutrient, method, and study quality [1] [4]. Some reviews warn that older studies have methodological shortcomings and that modern equipment may yield different outcomes [7] [4].

Conclusion — how to read these findings for consumers and policy

Pasteurization measurably reduces certain heat-sensitive vitamins and some bioactive proteins, but the peer-reviewed syntheses in these sources characterize overall nutritive loss as small and highlight the dominant public-health benefit of preventing foodborne disease [1] [9]. If your priority is a single percentage figure for “phytonutrients eliminated,” available sources do not provide that consolidated number; to get one would require meta-analysis focused specifically on the compounds you mean and on the exact pasteurization method in question [1] [4].

Want to dive deeper?
How does pasteurization affect specific phytonutrients like carotenoids and flavonoids in milk?
What are the differences in nutrient retention between pasteurized, ultra-pasteurized, and raw milk?
Does homogenization combined with pasteurization change the bioavailability of milk phytonutrients?
What pasteurization temperatures and times minimize loss of milk phytonutrients?
Are there health risks that outweigh nutrient differences when choosing raw versus pasteurized milk?