Which sexual‑enhancement supplements have been recalled or found to contain prescription drugs since 2010?
Executive summary
Since 2010 dozens of sexual‑enhancement products marketed as “natural” dietary supplements have been recalled or publicly warned about after laboratory testing found undeclared prescription drugs—most commonly PDE‑5 inhibitors such as sildenafil (Viagra) and tadalafil (Cialis), but also vardenafil, dapoxetine, and other pharmaceuticals and analogues [1] [2]. FDA public notifications and recalls have repeatedly named specific products (for example MR.7 SUPER 700000, ENDUREA, VITALITY, and various “Ram It”/“To The Moon” products) and broader multi‑brand actions, underscoring a persistent market problem rather than isolated incidents [3] [2] [4] [5] [6].
1. The headline offenders named by the FDA and consumer watchdogs
FDA laboratory analyses and recall notices since 2010 have specifically identified and removed or warned against products such as MR.7 SUPER 700000 (found to contain sildenafil and tadalafil) [3] [7], ENDUREA (confirmed to contain tadalafil and sildenafil) [2], VITALITY/Vitality capsules (tainted with sildenafil and tadalafil and subject to recall/consumer alerts) [4] [8], and male‑enhancement blister‑pack products marketed as “Ram It” & “To The Moon” that were recalled for the presence of sildenafil/tadalafil [5]. ConsumerLab and news outlets also flagged multi‑brand recalls in 2024 when Pyramid Wholesale pulled 11 brands after testing showed undeclared sildenafil and tadalafil [6] [9].
2. Beyond Viagra and Cialis—other prescription drugs and analogues found
Academic reviews and FDA databases show the adulteration problem extends beyond classic PDE‑5 inhibitors: a systematic analysis of adulterated supplements listed dapoxetine (an antidepressant not approved in the U.S.) in multiple sexual‑enhancement products and detected sibutramine—a weight‑loss drug pulled from the U.S. market in 2010—in at least two sexual‑enhancement products [1]. Studies and surveillance testing have also identified vardenafil and numerous structural analogues of PDE‑5 inhibitors across the tainted product pool, indicating manufacturers sometimes use modified molecules to evade detection and regulation [1] [10].
3. Patterns across recalls and FDA warnings: repeat offenders and supply chains
Regulatory and research sources show a recurring pattern: many adulterated products originate outside the U.S. or enter through international mail, adulteration often persists even after public warnings, and a substantial share of flagged items contain multiple hidden drugs in a single product—one review found 18.4% of adulterated sexual‑enhancement supplements contained more than one hidden drug ingredient [10] [1]. Investigations have found that recalled or warned‑about products sometimes remain available online months after notices, complicating consumer protection [10] [11].
4. Health risks and why regulators act—interactions, dosages, and unknowns
The FDA and public‑health researchers emphasize that undeclared sildenafil, tadalafil, vardenafil, and analogues pose real dangers—most notably severe blood‑pressure drops when combined with nitrates used for cardiac conditions—and that consumers cannot safely dose or anticipate interactions when pharmaceuticals are hidden in supplements [3] [7] [2]. The presence of other drugs like dapoxetine or sibutramine introduces further cardiovascular and psychiatric risks because these agents were never disclosed on labels and lack dosing oversight in over‑the‑counter products [1].
5. How complete is the public record and what’s left unanswered
Publicly available FDA notifications, academic surveys, and watchdog reporting document many named recalls and warnings but do not create a single exhaustive list of every tainted product since 2010; academic reviews and FDA databases capture hundreds of adulterated samples and recurring detection of specific drugs, yet sampling is opportunistic and market turnover means new adulterated formulations can reappear under new brands [1] [10] [12]. Therefore, while specific named products (MR.7 SUPER 700000, ENDUREA, VITALITY, Ram It/To The Moon, Rhino 69 Extreme and the multi‑brand Pyramid Wholesale recall) exemplify the problem, the reporting makes clear that these are representative examples in a larger, ongoing contamination trend rather than a closed inventory [3] [2] [4] [10] [6].