How do St. Jude’s reserve levels and fundraising expenditures compare to peer pediatric research hospitals?

Checked on February 1, 2026
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Executive summary

St. Jude holds unusually large reserves and raises far more in donations than most peer pediatric research hospitals, a difference that reporting shows is large enough to exceed the combined fundraising of several highly ranked cancer centers; St. Jude cites prudent financial planning and upcoming capital projects, while critics argue those reserves worsen funding competition for other pediatric research programs [1] [2] [3]. Available documents show St. Jude publicly reports its audited combined financial statements and annual reports and defends its reserve build-up as a buffer against economic shocks and to fund future capital needs [4] [5] [6].

1. How big are St. Jude’s reserves, in plain numbers

Investigations found St. Jude reported nearly $886 million in unspent revenue in a single recent year and has amassed multi‑billion‑dollar fundraising totals in campaigns that set single‑fiscal‑year records for the institution — figures ProPublica used to illustrate that St. Jude’s reserves have “ballooned” even as families and some researchers press for more distributed funding for pediatric work [1] [2]. St. Jude’s own audited combined financial statements and annual report document the hospital and ALSAC’s balance sheet positions and confirm the organization publicly discloses its finances under GAAP and independent audits [4] [5] [6].

2. How that reserve level compares with peers

ProPublica’s analysis points to a stark fundraising gap: in 2020 St. Jude reportedly pulled in more than the combined total of the nine hospitals ranked above it in U.S. News’s pediatric cancer rankings, a data point used to demonstrate that St. Jude’s financial scale outstrips many peer institutions [1]. The reporting emphasizes scale rather than a line‑by‑line apples‑to‑apples reserve comparison, and the sources provided do not include a systematic, audited table of competing hospitals’ reserve balances, so precise parity comparisons of reserve ratios across peers cannot be independently verified from the documents at hand [1] [7].

3. Fundraising expenditures and how they’re spent

St. Jude’s public materials state that a high proportion of donations support research, treatment and operations, and that fundraising supports both ongoing operations and planned capital projects such as family housing and research space; St. Jude’s site says 82 cents of every donated dollar over seven years went to mission activities while the remainder funded fundraising and administration, and their financial statements outline planned construction projects like Domino’s Village and Family Commons [8] [3] [5]. ProPublica notes the hospital was raising billions for new construction but, at the time of reporting, did not plan to spend the reserve directly on those new facilities — an important distinction between cash on hand and earmarked capital campaigns [2] [1].

4. The critique from peers, researchers and families

Researchers, oncologists and advocacy groups quoted in reporting argue that St. Jude’s outsized fundraising and reserves can crowd donor attention and philanthropic dollars away from other children’s hospitals that run pediatric cancer trials and require donations to support staff and research, and families reported gaps in nonmedical supports even as institutional reserves grew [2] [1]. ProPublica’s coverage documents families still incurring housing, travel and food expenses and notes St. Jude historically relied on referrals to smaller charities for some family needs — a practice the hospital says it has amended after scrutiny [2] [1].

5. St. Jude’s defense and stated strategy

St. Jude and ALSAC defend reserve accumulation as prudent long‑term planning to guard against market swings and geopolitical shocks and to ensure future operating and capital needs are met; the hospital also highlights independent charity ratings and audited financials to bolster claims of fiscal responsibility [1] [6] [8]. The organization points to specific future commitments — expanded collaborations, construction projects, and planned increases in operating costs through 2026 — as the rationale for maintaining significant liquidity [3] [1].

6. What can be concluded and what remains unresolved

The available reporting establishes that St. Jude’s reserves and fundraising scale are substantially larger than many peer pediatric research hospitals and that this reality has prompted both internal reforms (expanded family supports) and external criticism about competitive effects on philanthropy for pediatric cancer nationwide [1] [2]. What remains unresolved in the provided sources is a standardized, publicly available comparison of reserve‑to‑expense ratios across peer institutions and a full audit of how unrestricted reserves versus restricted campaign funds are being allocated across future projects, a gap that limits definitive cross‑institutional judgments without further financial disclosures from peers [7].

Want to dive deeper?
How do reserve-to-expense ratios at other major pediatric research hospitals (Boston Children's, Seattle Children's, Nationwide) compare to St. Jude?
What rules govern nonprofit hospital reserve levels and donor restrictions, and how do auditors treat large charitable reserves?
How have St. Jude’s family support policies changed since ProPublica’s reporting and what specific financial aid is now provided directly by the hospital?