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Are there any clinical trials or studies on Total Package Serum?

Checked on November 15, 2025
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Executive summary

Sun Coast Sciences/Del Mar’s Total Package Serum is repeatedly described online as “clinically tested” and the brand’s marketing cites specific study-style outcomes (for example, a 12‑week 10% brightness gain and Argireline reducing wrinkles 17% in 15 days) [1] [2]. Independent outlets and several reviews, however, say the company does not publish clear, independent clinical trial data for the finished product and that many claims appear to rely on ingredient-level studies or manufacturer‑sponsored testing rather than peer‑reviewed trials of the serum itself [3] [4] [5].

1. What the brand and product pages claim — specific study numbers and timelines

Sun Coast Sciences / Del Mar product pages and affiliated “official” sites state clinical outcomes for the product or key ingredients: a 12‑week study with a 10% improvement in skin brightness, visible changes in 14 days tied to the serum’s ingredients, and a claim that Argireline produced a 17% wrinkle reduction in 15 days [1] [6] [2] [4]. These are repeated across multiple company-controlled pages and marketing writeups [1] [6] [4].

2. Independent reviews’ take — ingredient evidence vs. finished‑product trials

Third‑party reviewers and ingredient analysts emphasize that many of Total Package Serum’s active components (e.g., acetyl hexapeptide‑8/Argireline, palmitoyl pentapeptide‑4/Matrixyl, sodium ascorbyl phosphate, hyaluronic acid) have clinical evidence supporting their effects when studied individually, but they note a lack of transparent, independent clinical trials published for the finished serum itself [7] [5] [3]. ConsumerHealthDigest specifically says the official site lacks clear mention of independent clinical trials or dermatologist testing [3].

3. Where the reporting overlaps — manufacturer‑sponsored vs. peer‑reviewed studies

Multiple listings state that “clinical” results exist but do not always link to peer‑reviewed papers or trial registries; incidental pages and reviews observe that much of the research cited appears manufacturer‑sponsored or ingredient‑level rather than randomized, placebo‑controlled trials of the marketed product [4] [5] [3]. That distinction matters for assessing how confidently one can attribute outcomes to the complete formula versus known effects of isolated ingredients.

4. Conflicting or promotional sources — marketing repetition and unverifiable specifics

Several promotional or review sites repeat specific numeric claims (e.g., “63% improvement in skin hydration,” “4.96‑star rating from 86,000 customers,” or clinical testing by “DermalTech Labs 2024”) without accessible original study documents or citations to journals, making it difficult to verify those exact figures from independent reporting [1] [8] [9]. Some pages conflate ingredient‑level trials (for example, Argireline or acetyl hexapeptide‑8 studies) with trials of the packaged product [2] [7].

5. What reviewers caution consumers to watch for

Reviewer outlets advise caution because the company’s claims are not always accompanied by public, independent trial reports or clear trial design details (sample size, controls, blinding), and they recommend interpreting brand claims accordingly and consulting health professionals when needed [3] [10]. One analysis notes that most cited research is manufacturer‑sponsored and suggests that while peptide research is “promising,” it isn’t the same as independent validation of the marketed serum [5] [10].

6. How to verify clinical trial claims yourself — a practical checklist

To confirm whether a true independent clinical trial of Total Package Serum exists, look for: (a) a link to a peer‑reviewed journal article or DOI on the product/brand site; (b) a ClinicalTrials.gov (or other registry) entry naming the finished product; (c) clear trial methodology (randomization, placebo/comparator, sample size, duration, endpoints); and (d) disclosure of sponsor/funder and conflicts of interest. Available sources do not mention a specific peer‑reviewed publication or registry entry for a randomized, independent clinical trial of the finished Total Package Serum product [3] [4].

7. Bottom line and context for consumers

There is ingredient‑level science behind several components in the formula and repeated marketing claims of clinical results for the serum, but the public record accessible in the reviewed sources does not show a clearly documented, independent clinical trial of the finished product; many claims appear on company or promotional pages and may be based on manufacturer‑sponsored testing or extrapolations from ingredient studies [1] [3] [5]. Consumers who want rigorous proof should request the trial protocol and published data from Sun Coast Sciences/Del Mar or look for independent peer‑reviewed studies before taking the brand’s headline percentages at face value [3] [4].

Want to dive deeper?
Has Total Package Serum undergone randomized controlled trials for safety and efficacy?
What active ingredients are in Total Package Serum and what clinical evidence supports them?
Have dermatologists or independent labs published peer-reviewed studies on Total Package Serum?
Are there consumer-reported adverse events or FDA/FTC actions related to Total Package Serum?
How does Total Package Serum compare in trials to comparable anti-aging or skin-repair serums?