Index/Organizations/ACTIV-6: COVID-19 Study of Repurposed Medications

ACTIV-6: COVID-19 Study of Repurposed Medications

Clinical trial

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6 results
Dec 21, 2025
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What high‑quality randomized trials have evaluated ivermectin for COVID‑19 and what were their results?

High‑quality randomized trials have largely failed to show clinically meaningful benefits of ivermectin for COVID‑19: several large, double‑blind, placebo‑controlled trials found no reduction in hospi...

Jan 16, 2026

What is the dose‑response relationship for ivermectin adverse events across controlled human trials?

Controlled human trials and systematic reviews conducted to date do not demonstrate a clear, consistent dose–response increase in adverse events for ivermectin across the common therapeutic range and ...

Jan 15, 2026

What randomized trials are currently registered to study long-term safety of ivermectin and what outcomes do they track?

A patchwork of randomized trials has evaluated ivermectin’s short‑term effects, but few registered RCTs explicitly set out to study long‑term safety; when long‑term endpoints are declared they most co...

Jan 4, 2026

What large randomized trials of ivermectin for COVID‑19 have reported since 2022 and what were their results?

Since 2022 several large, randomized, controlled trials and platform studies have reported on ivermectin for COVID‑19 and the aggregate finding from those high‑quality trials is a lack of clinically m...

Oct 18, 2025

What are the FDA guidelines for using ivermectin to treat COVID-19?

The FDA has not authorized or approved ivermectin for the treatment or prevention of COVID‑19; its official position is that ivermectin should not be used for COVID‑19 outside of a clinical trial beca...

Oct 17, 2025

ivermectine and covid

Large, high-quality randomized trials and recent meta-analyses converge on the conclusion that in outpatient settings, with no reliable evidence of reduced hospitalization or mortality and only incons...