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Mammalian proteins found in Homo sapiens
Two monoclonal antibodies—lecanemab (Leqembi) and donanemab (Kisunla)—offer modest slowing of early Alzheimer’s symptoms but carry specific, sometimes serious safety risks that require structured moni...
Toxoplasma gondii is a neurotropic parasite that establishes long-term, often latent, infections in the brain and has been repeatedly implicated in altered cognition; animal experiments show clear eff...
Clinical algorithms to pause or restart anti‑amyloid monoclonal antibody therapy after amyloid‑related imaging abnormalities (ARIA) hinge on two parallel axes: radiologic severity on standardized MRI ...
Anti‑amyloid monoclonal antibodies differ in what forms of Aβ they bind, how much they lower brain amyloid and downstream biomarkers, and in clinical benefit versus risk balance: lecanemab targets sol...