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Scientific journal covering theoretical, observational, and instrumental astronomy and astrophysics
The available evidence does not show that Dr. Mehmet Oz supports an organization or product called “APEX FORCE.” None of the provided sources link Dr. Oz to APEX FORCE; instead they either note ASTRO ...
When prostate-specific antigen (PSA) rises after radical prostatectomy, major specialty guidelines and recent studies conclude that , with consensus language endorsing offering SRT at or below commonl...
After radical prostatectomy, major guidelines and expert bodies expect PSA to fall to undetectable levels within weeks to a few months and use low numerical thresholds and serial rises to define bioch...
Three major prostate‑cancer guideline bodies—NCCN, AUA, and EAU—agree on the central role of serial PSA after radical prostatectomy but diverge on measurement sensitivity, timing of intervention, imag...
Guidelines permit, but do not mandate, use of ultrasensitive PSA (usPSA) after radical prostatectomy: the AUA/ASTRO/SUO panel says clinicians may obtain usPSA in patients at high risk of recurrence wh...
Ultrasensitive PSA (uPSA) assays detect levels well below conventional thresholds (commonly <0.1 ng/mL and in some assays down to ~0.003–0.001 ng/mL), and studies show lower uPSA nadirs and early rise...
Guidelines recommend considering salvage radiation therapy (SRT) earlier rather than later because multiple large datasets show better outcomes when SRT is given at lower PSA — with common thresholds ...
Biochemical recurrence that is suspected or imaged without a concomitant rise in standard PSA levels is unusual but documented, and management balances early salvage intent against risks of overtreatm...
No single, universally accepted PSA cutoff mandates salvage radiotherapy (sRT) after radical prostatectomy, but contemporary evidence and guidelines converge on “the earlier the better” — many studies...
Randomized trials and large observational studies find that early (immediate or "early salvage") radiotherapy after biochemical recurrence generally lowers the risk of later metastasis versus delayed ...
Biochemical recurrence (BCR) after radical prostatectomy is most commonly defined as a postoperative serum PSA of , a standard adopted in AUA guidance and reiterated in contemporary literature; that d...
After radical prostatectomy, major guideline documents emphasize detecting a *detectable* PSA early because salvage radiotherapy is more effective at low PSA levels (≤0.5 ng/mL), but they do converge ...