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Index/Organizations/Beckwith-Wiedemann syndrome

Beckwith-Wiedemann syndrome

Syndrome characterized by overgrowth (macrosomia), an increased risk of childhood cancer and congenital malformations

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Dec 6, 2025
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What medical definitions classify penile macropenis or micropenis and how common are they?

Medical definitions use standardized stretched penile length (SPL) cutoffs—commonly 2.5 standard deviations (SD) from the population mean—to define both micropenis (SPL ≤ −2.5 SD) and macropenis/megal...

Jan 22, 2026

What causes have been reported for macrophallia (endocrine, tumors, congenital)?

— clinically noted as an abnormally large penis — has been reported in the literature as arising from three broad groups of causes: endocrine-driven tissue overgrowth (most classically growth‑hormone ...