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each carry subgroup data from randomized trials and growing real-world cohorts that examine visceral vs non‑visceral disease, endocrine‑sensitivity, menopausal status, molecular subtype (e.g., luminal...
Ribociclib’s quality-of-life (QoL) evidence is relatively strong in the sense that its pivotal reported maintained HR‑QoL alongside consistent overall‑survival (OS) advantages, and guideline/health‑te...
, as tested in the program, is the only CDK4/6 inhibitor with consistent, statistically significant overall survival (OS) advantages reported across multiple phase III trials (MONALEESA‑2, ‑3, and ‑7)...
mRNA COVID-19 vaccines differ from many traditional vaccines by delivering instructions (mRNA) that tell cells to make a viral protein and thereby stimulate both innate and adaptive immunity; recent s...
COVID-19 mRNA vaccines are associated in recent studies with when given near the start of immune checkpoint therapy, and several observational and experimental reports link vaccination to improved sur...