Index/Organizations/EudraVigilance

EudraVigilance

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13 results
Dec 6, 2025
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How do long-term side effects of the J&J vaccine compare with mRNA COVID-19 vaccines?

Large surveillance studies and safety summaries show different rare long‑term risks for the Janssen (J&J) adenovirus vaccine versus mRNA vaccines: J&J has been associated with rare thrombosis with thr...

Nov 26, 2025
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What long-term side effects have been documented for mRNA COVID-19 vaccines like Pfizer and Moderna?

Large safety reviews and surveillance systems report that most consequences of Pfizer and Moderna mRNA COVID-19 vaccines are short‑lived (local pain, fatigue, fever) but rare serious events have been ...

Jan 14, 2026
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What are the documented side effects of tirzepatide in clinical trials and real‑world reports?

Clinical trials and pooled analyses consistently identify gastrointestinal effects — especially nausea, diarrhea, vomiting and constipation — as the most common adverse reactions to tirzepatide, while...

Nov 24, 2025

How do vaccine adverse event reporting systems (VAERS, Yellow Card, EudraVigilance) differentiate reports from confirmed vaccine-caused deaths?

Vaccine adverse event reporting systems such as VAERS (U.S.), the UK Yellow Card, and EudraVigilance collect reports of events that happen after vaccination but do not by themselves confirm that a vac...

Jan 5, 2026

What serious adverse event signals (pancreatitis, thyroid, eye) have been reported for tirzepatide in FAERS and EudraVigilance, and how should clinicians interpret disproportionality findings?

Post-marketing pharmacovigilance analyses of tirzepatide identify disproportionate reporting for pancreato-biliary events (including pancreatitis), thyroid-related events, and eye-related events acros...

Jan 5, 2026

What are the most common adverse events and discontinuation rates for tirzepatide in real‑world cohorts?

Real‑world pharmacovigilance and observational studies consistently identify gastrointestinal events—nausea, vomiting, diarrhea, constipation and dyspepsia—as the most common adverse events (AEs) with...

Dec 16, 2025

Are there psychiatric side effects (depression, suicidal ideation) reported with tirzepatide use?

Pharmacovigilance and recent reviews report psychiatric adverse events (AEs) — including depressive symptoms and suicidal thoughts — in users of GLP‑1 receptor agonists and tirzepatide, but reports ar...

Dec 16, 2025

Are there psychiatric or CNS drug interactions to watch for with tirzepatide?

Available reporting shows no clear pharmacokinetic CNS‑drug interactions unique to tirzepatide but does document psychiatric adverse events in real‑world surveillance and case reports that clinicians ...

Dec 2, 2025

Do 5-alpha-reductase inhibitors (finasteride, dutasteride) cause decreased libido or erectile dysfunction long-term?

Clinical trials and meta-analyses find that oral 5‑alpha‑reductase inhibitors (5‑ARIs) — finasteride and dutasteride — increase the risk of sexual adverse events (erectile dysfunction, decreased libid...

Dec 1, 2025

What are the common side effects, risks, and long-term safety data for tirzepatide?

Tirzepatide commonly causes gastrointestinal side effects—nausea, vomiting, diarrhea—more often than placebo and leads to higher discontinuation at higher doses (OR for AEs 1.34; discontinuation OR 2....

Dec 1, 2025

What neurological long-term effects, if any, have been reported after Janssen vaccination up to 2024?

Reports through 2024 link Janssen’s Ad26.COV2.S (J&J/Janssen) vaccine to rare immune-mediated neurological events, most consistently Guillain–Barré syndrome (GBS); U.S. safety reviews found an increas...

Nov 26, 2025

Which populations, if any, faced increased risk of severe adverse outcomes after COVID-19 vaccination and why?

Large, high-quality surveillance and guideline reviews conclude COVID‑19 vaccines have rare but identifiable serious risks in specific groups — most notably myocarditis/pericarditis in younger males a...

Nov 7, 2025

How do neurological adverse event reports after COVID vaccination compare to rates after COVID infection (2021-2024)?

The three documents provided contain no substantive data on neurological adverse events after COVID vaccination or after COVID infection for 2021–2024, so . Each source addresses unrelated technical t...