Index/Organizations/JAMA Oncology

JAMA Oncology

Monthly peer-reviewed medical journal published by the American Medical Association. It covers all aspects of medical oncology, radiation oncology, and surgical oncology, as well as subspecialties

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13 results
Dec 14, 2025
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Can a rising PSA level after prostate cancer surgery be a false positive?

A rising PSA after radical prostatectomy usually signals remaining prostate tissue—most often recurrent cancer—but timing and test sensitivity matter: guidelines and studies warn that PSA can persist ...

Dec 2, 2025
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How soon after prostate surgery should PSA be measured and how often thereafter?

Recent studies and guideline summaries show clinicians have routinely checked PSA 6–8 weeks (1.5–2 months) after radical prostatectomy, but new large analyses argue waiting at least three months reduc...

Nov 27, 2025
Most Viewed

What is the significance of a PSA spike after robotic prostate surgery?

A rising or “spike” in PSA after robotic (or any) radical prostatectomy can mean different things: persistent or recurrent prostate cancer, residual benign prostate tissue, or simply timing/measuremen...

Dec 9, 2025

How soon after prostatectomy should PSA be monitored to detect biochemical recurrence?

Recent large-cohort evidence and guideline summaries disagree about the ideal timing for the first definitive post‑prostatectomy PSA check: traditional practice often measures PSA at about 1.5–2 month...

Jan 15, 2026

What randomized trials are underway testing PSMA PET–guided salvage radiotherapy and when will results be reported?

Three categories of randomized trials are actively testing whether PSMA PET–guided changes to salvage radiotherapy improve outcomes: a completed/phase‑II randomized study reported in meetings with a f...

Dec 11, 2025

What is the typical timeline for PSA to become undetectable after radical prostatectomy?

PSA usually falls to very low or undetectable levels after radical prostatectomy within about 4–12 weeks; multiple authorities say roughly 4–8 weeks or "about two months," while some cohort data repor...

Dec 7, 2025

What is the significance of PSA levels at 3 months post-prostatectomy?

New large-cohort data and multiple clinical guides agree that PSA should fall to very low or undetectable levels after radical prostatectomy, but measuring PSA too early (around 1.5–2 months) can misc...

Dec 6, 2025

How long does it take for PSA to reach undetectable levels after prostatectomy?

After radical prostatectomy, most clinical sources say PSA falls to very low or undetectable levels within weeks to a few months — commonly cited windows are “within a couple of months” or roughly 6–8...

Dec 1, 2025

What are typical PSA monitoring guidelines post-prostatectomy?

Current professional guidance typically calls for frequent PSA checks after radical prostatectomy—commonly every 3 months in the early years and then less often—while recent large-cohort data argue wa...

Nov 30, 2025

What factors delay PSA stabilization after prostate surgery?

PSA usually falls to very low or undetectable levels within about 4–8 weeks after radical prostatectomy, because the main PSA source (the prostate) has been removed . New large-cohort analyses argue w...

Nov 30, 2025

What is the expected PSA timeline in the first year after radical prostatectomy?

After radical prostatectomy (RP) PSA typically falls to a very low or undetectable level within about 2 months, but recent large-cohort research and several specialist bodies argue for waiting at leas...

Nov 29, 2025

How long does it take for PSA levels to stabilize after prostate surgery?

Major clinical guidance and recent studies agree that PSA usually falls to very low or undetectable levels after radical prostatectomy, but the timing varies: traditional advice is to wait 6–8 weeks (...

Nov 2, 2025

How soon after radical prostatectomy should PSA be measured (weeks/months)?

After radical prostatectomy, , with multiple studies and expert sources recommending at least a 3-month window before interpreting persistent PSA to avoid overtreatment and to identify true biochemica...