Index/Organizations/National Comprehensive Cancer Network

National Comprehensive Cancer Network

Non-profit organization in the USA

Fact-Checks

23 results
Dec 2, 2025
Most Viewed

How do ultrasensitive PSA tests differ from standard assays and how should results be interpreted post‑op?

Ultrasensitive PSA (uPSA) assays detect PSA at levels below 0.1 ng/mL — in some labs down to ~0.001–0.006 ng/mL — and so can identify biochemical recurrence earlier than standard assays, which typical...

Jan 12, 2026
Most Viewed

Guidelines for PSA testing frequency after prostatectomy?

After radical prostatectomy, the first PSA check is usually delayed until the immediate postoperative PSA has cleared (commonly 6–8 weeks), and major guideline frameworks recommend more frequent testi...

Dec 12, 2025
Most Viewed

Can horse paste be used as a topical treatment for basal cell carcinoma?

There is no credible clinical evidence in the provided sources that “horse paste” (ivermectin formulations intended for animals) is an established topical treatment for basal cell carcinoma (BCC). Maj...

Jan 16, 2026

How do oncology guideline bodies (NCCN, ESMO, ASCO) formally address repurposed antiparasitic drugs in recent statements?

No explicit, formal endorsements or dedicated recommendations for repurposed antiparasitic drugs appear in the recent guideline summaries and updates from the National Comprehensive Cancer Network (NC...

Jan 12, 2026

What are guideline differences between NCCN, AUA, and EAU on post‑prostatectomy PSA surveillance and why?

Three major prostate‑cancer guideline bodies—NCCN, AUA, and EAU—agree on the central role of serial PSA after radical prostatectomy but diverge on measurement sensitivity, timing of intervention, imag...

Jan 22, 2026

How should management (staging, systemic therapy, trials) change for patients with high‑grade prostate cancer and very low PSA?

(Grade Group 4–5 or Gleason ≥8) with a deceptively low serum PSA should trigger more aggressive staging and consideration of treatment intensification rather than reassurance; modern imaging (includin...

Jan 21, 2026

How do the American Urological Association and NCCN define biochemical recurrence PSA thresholds after prostatectomy?

defines (BCR) after radical as a postoperative prostate‑specific antigen (PSA) of ≥0.2 ng/mL confirmed by a second PSA ≥0.2 ng/mL, a threshold used to standardize reporting and guide consideration of ...

Dec 13, 2025

What is the analytic sensitivity and specificity of ultrasensitive PSA tests compared to standard assays?

Ultrasensitive PSA (uPSA) assays lower analytical detection limits from the conventional ~0.1–0.2 ng/mL down to the 0.003–0.001 ng/mL range in some platforms; manufacturers and reviews report lower li...

Dec 2, 2025

What PSA threshold indicates biochemical recurrence after prostate removal?

There is no single universally agreed PSA cut‑off after radical prostatectomy that defines biochemical recurrence; many expert groups and major centres use two consecutive values ≥0.2 ng/mL as the pra...

Feb 5, 2026

what is the recent combination therapy with Ribociclib from novartis demonstrating potential strong efficacy in 1L metastatic breast cancer?

(Kisqali) combined with an aromatase inhibitor—most commonly letrozole—has emerged as a standout first‑line (1L) combination therapy for hormone‑receptor–positive (HR+), HER2‑negative metastatic breas...

Feb 5, 2026

where do ribociclib, palbociclib and abemaciclib sit in treatment guidelines?

Three —, and —sit firmly as the standard first-line systemic option for HR‑positive, HER2‑negative advanced/metastatic breast cancer when combined with endocrine therapy, with guideline bodies and ran...

Feb 5, 2026

how robust is ribociclib's safety and tolerability data compared to palbociclib and abemaciclib

and tolerability profile is well characterized across randomized trials, meta-analyses and , and shows a distinct pattern—predominantly hematologic and hepatic risks with a known signal for QTc prolon...

Feb 1, 2026

How do MONALEESA trial overall survival results for ribociclib compare with other CDK4/6 inhibitors in HR+/HER2- metastatic breast cancer?

, as tested in the program, is the only CDK4/6 inhibitor with consistent, statistically significant overall survival (OS) advantages reported across multiple phase III trials (MONALEESA‑2, ‑3, and ‑7)...

Feb 1, 2026

Does kisqali improve outcomes for ER positive HER negative metastatic breast cancer?

(ribociclib), a CDK4/6 inhibitor taken with endocrine therapy, improves key outcomes for people with ER‑positive, HER2‑negative metastatic breast cancer: randomized trials show meaningful increases in...

Jan 23, 2026

Which pharmacologic or lifestyle interventions have been shown to prevent or reverse radiation-induced bone loss in cancer survivors?

causes measurable bone injury through cell damage, vascular injury and altered remodeling that can produce focal insufficiency fractures and in cancer survivors . The strongest, actionable evidence su...

Jan 4, 2026

What treatment and monitoring strategies are recommended for patients with biochemical recurrence without PSA rise?

Biochemical recurrence that is suspected or imaged without a concomitant rise in standard PSA levels is unusual but documented, and management balances early salvage intent against risks of overtreatm...

Dec 19, 2025

How do mainstream medical guidelines assess the therapies promoted by Pete Sulack?

The materials provided describe Pete Sulack as a proponent of faith‑infused functional medicine who promotes integrative protocols including orthomolecular support, hyperbaric oxygen, lifestyle change...

Dec 12, 2025

Have major oncology clinical guidelines (NCCN, ESMO, ASCO) updated recommendations based on ivermectin cancer trials?

Major oncology guideline bodies (NCCN, ESMO, ASCO) have not adopted ivermectin as a recommended cancer treatment; available sources report only early-phase trials and preclinical work, with one active...

Dec 9, 2025

What clinical guidelines or professional organizations dispute the safety or effectiveness of treatments advocated by Dr. Pete Sulack?

Dr. Pete Sulack promotes cancer approaches that mix repurposed antiparasitic drugs (ivermectin, mebendazole, fenbendazole), orthomolecular supplements, detoxification and faith-driven care; his site a...

Dec 9, 2025

What are the diagnostic criteria and measurement thresholds for macrophallia in urology?

There are no references to “macrophallia” or diagnostic thresholds for penile size in the provided urology sources; the search results instead concern hematuria, bladder and prostate cancer guidelines...