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Index/Organizations/Obesity Reviews

Obesity Reviews

Peer-reviewed scientific journal

Fact-Checks

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Jan 18, 2026

What randomized evidence exists on sustained remission after GLP‑1 or GLP‑1/GIP agonist therapy withdrawal?

Randomized trial evidence and several recent systematic reviews show that clinically meaningful weight loss achieved with GLP‑1 and GLP‑1/GIP agonists is frequently lost after drug withdrawal—with mos...

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