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World Health Organization drug safety database
Drug‑induced liver injury (DILI) from ivermectin in humans is , primarily in case reports and pharmacovigilance datasets rather than large prospective studies. Available evidence shows occasional seri...
Available reports show ivermectin is usually well tolerated at standard single-dose regimens but has documented, rare cases of clinically apparent liver injury and even fulminant liver failure after n...
Case series, pharmacovigilance data and isolated case reports describe ivermectin‑associated hepatic injury ranging from asymptomatic transaminase elevations to fulminant hepatitis; most published sig...
Ivermectin in adults is associated with a spectrum of recognized adverse reactions that can be neurological (confusion, seizures, encephalopathy) and allergic or cutaneous (rash, pruritus, severe hype...
Serious adverse reactions reported with ivermectin include neurologic events (encephalopathy, confusion, coma), severe cutaneous reactions (Stevens–Johnson syndrome, toxic epidermal necrolysis, DRESS)...
There are no single, global "official guidelines" that specifically prescribe ivermectin use in people with chronic liver disease; major drug references and pharmacovigilance reports advise caution an...