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The effectiveness of the 2025-2026 influenza vaccine against the dominant H3N2 subclade K
The 2025–2026 influenza vaccine provides meaningful protection overall but is an imperfect match against the currently dominant H3N2 subclade K; early estimates show strong protection against severe o...
The provides meaningful protection against the circulating H3N2 viruses but is imperfect against the newly dominant : antigenic studies show reduced reactivity to subclade K versus the vaccine referen...
Early, multi-country data indicate the 2025–2026 seasonal vaccines provide meaningful but imperfect protection against the emergent H3N2 J.2.4.1 (subclade K): strong protection in children (roughly 72...