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Index/Topics/5α-reductase Inhibitors

5α-reductase Inhibitors

A class of drugs that inhibit the 5-α-reductase enzyme

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Jan 13, 2026
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What randomized or mechanistic studies exist on ejaculation frequency and prostate inflammation or DHT signaling?

Randomized clinical trials directly testing whether changing ejaculation frequency alters prostate inflammation or DHT signaling are essentially absent; most human evidence comes from observational co...

Jan 20, 2026

How effective are finasteride and minoxidil at restoring hair versus preventing further loss, according to clinical studies?

Clinical trials and meta-analyses show finasteride is principally effective at halting androgenetic hair loss and maintaining existing follicles, with modest capacity to increase terminal hair counts ...