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Index/Topics/Advanced Glycation End-Products (AGEs)

Advanced Glycation End-Products (AGEs)

The formation of Advanced Glycation End-Products (AGEs) and their impact on molecular function and signaling pathways.

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Jan 9, 2026

How does methylglyoxal (MGO) in Manuka honey influence systemic metabolism and are there measured effects on insulin signaling in humans?

Methylglyoxal (MGO) is the reactive dicarbonyl largely responsible for Manuka honey’s antibacterial reputation, and biochemically it is a potent glycating agent that can form advanced glycation end‑pr...

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