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Index/Topics/Alpha-lipoic acid for diabetic peripheral neuropathy

Alpha-lipoic acid for diabetic peripheral neuropathy

The effectiveness of alpha-lipoic acid in treating diabetic peripheral neuropathy compared to standard pharmacologic therapies.

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3 results
Feb 1, 2026
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What randomized trials compare alpha‑lipoic acid versus standard pharmacologic treatments for diabetic peripheral neuropathy?

Randomized trials of (ALA) for diabetic peripheral neuropathy overwhelmingly test ALA versus placebo or vitamins, not versus first‑line symptomatic drugs; intravenous ALA shows short‑term benefit whil...

Feb 1, 2026
Most Viewed

Are there randomized head‑to‑head trials comparing oral alpha‑lipoic acid monotherapy with pregabalin or duloxetine for painful diabetic neuropathy?

No high‑quality randomized, head‑to‑head trials directly comparing oral alpha‑lipoic acid (ALA) monotherapy with or for (PDN) have been identified in the provided literature; most randomized trials of...

Feb 7, 2026

What dosage of alpha-lipoic acid is recommended for neuropathy relief?

Clinical trials and meta-analyses most consistently show symptomatic benefit for at about 600 mg of alpha‑lipoic acid (ALA) per day, whether given orally or intravenously, with the strongest randomize...

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