Index/Topics/Alzheimer's drug pipeline

Alzheimer's drug pipeline

The development and review of drugs for treating Alzheimer's disease, including 182 clinical trials and 138 drugs in 2025

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7 results
Jan 16, 2026
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What are the long-term neurological and cognitive effects reported with chronic low-dose methylene blue use?

Clinical and preclinical literature describes repeated low-dose methylene blue (MB) as a candidate neuroprotective and memory‑enhancing agent via mitochondrial and anti‑oxidant actions, with human ima...

Jan 27, 2026
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What dose ranges and formulations (hydromethylthionine vs methylene blue) have different safety and absorption profiles in human studies?

Two chemically related agents — classical (methylthioninium chloride, MTC) and a stabilized reduced derivative called hydromethylthionine (HMT; marketed as hydromethylthionine mesylate, HMTM or TRx023...

Jan 24, 2026
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What peer‑reviewed clinical trials exist for Bacopa monnieri, Lion’s Mane, and huperzine‑A in cognitive outcomes?

has a modest but consistent randomized clinical-trial footprint showing small improvements on some memory and attention tests across multiple placebo‑controlled trials and meta‑analyses . The current ...

Jan 18, 2026

How do alternative remedies with honey compare to FDA-approved dementia drugs?

Honey shows biological properties—antioxidant, anti-inflammatory, and polyphenol-driven activities—that lab studies and animal models suggest could be neuroprotective and might modestly affect pathway...

Jan 14, 2026

Which approved dementia treatments are most effective compared to what Musk has promoted?

Approved, peer‑tested dementia treatments that have shown measurable slowing of cognitive decline in human trials remain the best-evidenced options today, while the interventions Elon Musk has promote...

Jan 23, 2026

What clinical trials exist for Huperzine‑A and its effects on memory in humans?

Clinical research on huperzine‑A () includes dozens of small randomized trials—many conducted in —and a multicenter U.S. phase II trial; pooled analyses report short‑term cognitive benefits in (AD) bu...

Jan 28, 2026

How does Neuropezil interact with other medications, supplements, or medical conditions?

appears to be the same pharmacologic agent as donepezil — a cholinesterase inhibitor used in that increases acetylcholine by inhibiting acetylcholinesterase . Its clinical risk comes less from foods a...