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Index/Topics/Amiodarone and Ivermectin Interaction

Amiodarone and Ivermectin Interaction

The interaction between amiodarone and ivermectin, including the risks of increased exposure and toxicity.

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Jan 24, 2026

Amiodarone

is a potent antiarrhythmic prescribed for life‑threatening ventricular arrhythmias and frequently used off‑label for when other drugs fail, but its efficacy is balanced by a wide range of organ toxici...

Jan 22, 2026

When should a patient on amiodarone avoid receiving ivermectin or similar drugs?

Patients taking should generally avoid coadministration of or “similar” drugs when the combination would raise ivermectin exposure (or amiodarone exposure) via P‑glycoprotein (P‑gp) or CYP-mediated pa...