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Index/Topics/Amyloid-related imaging abnormalities (ARIA)

Amyloid-related imaging abnormalities (ARIA)

A condition that can occur in people taking anti-amyloid antibodies, characterized by brain swelling or bleeding

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2 results
Jan 16, 2026

What are the common side effects and monitoring requirements for lecanemab and donanemab?

Lecanemab and donanemab are monoclonal anti‑amyloid antibodies approved for early Alzheimer’s disease that produce modest slowing of decline but carry important and common safety risks—most notably am...

Jan 15, 2026

What are clinical management algorithms (imaging thresholds and symptom criteria) for pausing or restarting anti‑amyloid therapy after ARIA is detected?

Clinical algorithms to pause or restart anti‑amyloid monoclonal antibody therapy after amyloid‑related imaging abnormalities (ARIA) hinge on two parallel axes: radiologic severity on standardized MRI ...