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ANCHOR Trial

The ANCHOR trial showed that detecting and treating anal HSIL in people with HIV reduces progression to anal cancer and that targeted screening in MSM with HIV is cost-effective.

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Jan 18, 2026

What are current screening recommendations for anal cancer in high‑risk groups such as HIV‑positive men who have sex with men?

New consensus and federal guidance now recommend targeted anal cancer screening for people with HIV, with men who have sex with men (MSM) and transgender women living with HIV offered lab‑based screen...