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Index/Topics/Antidiabetics Interaction

Antidiabetics Interaction

Berberine's interaction with antidiabetic drugs, such as insulin, sulfonylureas, and metformin, which can cause hypoglycemia.

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3 results
Jan 17, 2026
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What specific prescription drugs are most likely to interact with berberine and how should doses be adjusted?

Berberine inhibits multiple drug‑metabolizing enzymes and transporters—most notably CYP3A4, CYP2D6, CYP2C9 and intestinal CES2/P‑gp—which creates credible interaction risk with several prescription dr...

Jan 19, 2026

What are the documented interactions between common diabetes drugs (metformin, insulin, sulfonylureas) and popular supplements like ginseng, berberine, or vitamin D?

Common supplements ginseng, berberine and vitamin D have documented biologic effects that can overlap with prescription diabetes drugs — producing additive glucose‑lowering, pharmacokinetic changes, o...

Jan 19, 2026

What peer‑reviewed evidence exists for supplements commonly marketed to support blood sugar, and are any proven to reverse type 2 diabetes?

A large body of peer‑reviewed research has tested many supplements that are marketed to “support blood sugar,” but high‑quality trials and meta‑analyses show at best modest, inconsistent effects for a...

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