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Index/Topics/Berberine Metabolites

Berberine Metabolites

The metabolites of berberine, such as berberrubine and palmatine, and their effects on GLP-1 secretion.

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Jan 5, 2026

What clinical evidence exists for berberine or probiotics increasing endogenous GLP‑1 secretion in humans?

Clinical and mechanistic studies show plausible pathways by which berberine and certain probiotics could raise GLP‑1 secretion, but controlled human trials demonstrating a reproducible, physiologicall...

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