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cardiovascular outcome trials

Trials that assess the cardiovascular outcomes of GLP-1 receptor agonists

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Jan 12, 2026
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How do GLP‑1 drugs affect cardiovascular risk markers while on treatment versus after discontinuation?

GLP‑1 receptor agonists improve multiple cardiovascular risk markers—weight, glycaemic control, blood pressure, lipids and inflammatory biomarkers—and reduce major adverse cardiovascular events (MACE)...

Jan 18, 2026

What randomized evidence exists on cardiovascular outcomes after planned discontinuation of GLP‑1 therapy?

Randomized trial data directly assessing cardiovascular outcomes after a planned, protocolized discontinuation of GLP‑1 receptor agonists are scarce: most randomized controlled trials (RCTs) report ca...