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Index/Topics/CBD and Warfarin Interaction

CBD and Warfarin Interaction

The interaction between CBD products and warfarin, including the potential for increased bleeding risk due to the inhibition of cytochrome P450 enzymes.

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2 results
Jan 16, 2026

Are direct oral anticoagulants (DOACs) subject to the same interaction risk with CBD as warfarin?

Cannabidiol (CBD) has documented pharmacokinetic interactions with warfarin, supported by case reports and mechanistic data linking CBD to inhibition of CYP enzymes that metabolize warfarin (notably C...

Jan 16, 2026

Cbd oil (grapeseed oil base) effects when taken with warfarin

CBD products have been reported to raise warfarin activity—most often by increasing INR and thus bleeding risk—likely via inhibition of cytochrome P450 enzymes that metabolize warfarin, but the eviden...

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