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A condition that can affect TTR and require more intensive sampling and algorithmized dose adjustments.
Two randomized clinical trials directly tested oral sodium bicarbonate for effects on endothelial function measured by brachial artery flow‑mediated dilation (FMD): a small 2018 pilot randomized cross...
The evidence linking long-term or increased risk is mixed: isolated case reports and small biopsy-proven nephropathies raise concern, while larger epidemiological and studies generally do not show a c...
Frequent, protocolized INR monitoring combined with model anticoagulation-clinic practices — standardized dosing algorithms, pharmacist- or APP-led management, point-of-care or home testing, and struc...
Patients with chronic kidney disease (CKD) or heavy polypharmacy require systematic renal monitoring when prescribed antiparasitic agents because impaired renal clearance and drug–drug interactions ch...