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CNS Depressants

The potential for ivermectin to interact with central nervous system depressants like benzodiazepines and barbiturates.

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Jan 10, 2026
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Does ivermectin interact pharmacologically with opioids or benzodiazepines to increase respiratory depression?

Ivermectin has biologic actions on GABAergic and benzodiazepine receptor systems in experimental models and public health agencies warn it can potentiate other central nervous system (CNS) depressants...

Feb 1, 2026

What are the recommended ED treatments for ivermectin-induced seizures and respiratory depression?

Emergency treatment of is primarily supportive: secure the airway and breathing (oxygen, intubation and mechanical ventilation as needed), manage with standard anticonvulsant protocols (initial benzod...