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Index/Topics/COVID-19 vaccine updates

COVID-19 vaccine updates

Public health agencies and organizations are updating COVID-19 vaccine policies and guidelines in response to evolving SARS-CoV-2 variants and lineages.

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Jan 22, 2026

How do SARS-CoV-2 variants like Omicron specifically reduce vaccine effectiveness and what lab and epidemiologic evidence supports immune escape?

Variants such as reduce vaccine effectiveness primarily by accumulating mutations in the Spike protein that change antibody binding sites, producing antigenic mismatch to vaccine-elicited antibodies a...

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