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Index/Topics/CYP Enzymes and CBD

CYP Enzymes and CBD

The inhibition of CYP enzymes by CBD and its potential impact on the metabolism of anticoagulants.

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Jan 16, 2026

Are direct oral anticoagulants (DOACs) subject to the same interaction risk with CBD as warfarin?

Cannabidiol (CBD) has documented pharmacokinetic interactions with warfarin, supported by case reports and mechanistic data linking CBD to inhibition of CYP enzymes that metabolize warfarin (notably C...

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