factually
Index/Topics/CYP3A4 Inhibitors

CYP3A4 Inhibitors

CYP3A4 inhibitors, such as ketoconazole and erythromycin, interacting with ivermectin.

Fact-Checks

2 results
Jan 8, 2026

Which commonly prescribed antifungals and antibiotics are strongest CYP3A4 inhibitors and how do they affect drug levels in older adults?

Two classes of commonly prescribed anti-infectives — certain systemic azole antifungals and macrolide antibiotics — are among the strongest clinically relevant inhibitors of cytochrome P450 3A4 (CYP3A...

Jan 8, 2026

Which common medications taken by seniors have clinically significant interactions with repeated-dose ivermectin?

Repeated-dose oral ivermectin can interact with a range of medications commonly taken by older adults, most notably blood thinners such as warfarin, strong CYP3A4 inhibitors (for example ketoconazole ...