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Index/Topics/Diabetic Complications

Diabetic Complications

The potential role of MGO in diabetic complications and vascular dysfunction.

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Jan 9, 2026

How does methylglyoxal (MGO) in Manuka honey influence systemic metabolism and are there measured effects on insulin signaling in humans?

Methylglyoxal (MGO) is the reactive dicarbonyl largely responsible for Manuka honey’s antibacterial reputation, and biochemically it is a potent glycating agent that can form advanced glycation end‑pr...

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