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Index/Topics/DOACs Interactions

DOACs Interactions

The interactions between direct oral anticoagulants (DOACs) and various supplements, including the potential for bleeding risk or altered drug levels.

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Jan 12, 2026

Which dietary supplements most frequently interact with antithrombotic and cardiovascular drugs, and what evidence supports those interactions?

Several widely used supplements—omega‑3 (fish oil), garlic, ginkgo biloba, ginger, ginseng, curcumin/turmeric, nattokinase, red yeast rice, vitamin K and vitamin E—are the supplements most frequently ...

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