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drug interactions

Drugs that inhibit CYP3A4 or inhibit P‑glycoprotein can raise ivermectin blood levels and therefore increase adverse‑effect risk, while strong inducers can lower efficacy.

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Jan 16, 2026
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What are the documented medical risks of regular oral sodium bicarbonate use (electrolytes, blood pressure, drug interactions)?

Regular oral use of sodium bicarbonate (baking soda) carries documented risks including metabolic alkalosis, disturbances in sodium, potassium and chloride balance, expansion of intravascular volume w...

Jan 12, 2026
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What drug interactions have been documented for Bacopa monnieri and how strong is the evidence?

Bacopa monnieri has been documented to interact with drugs primarily by inhibiting multiple cytochrome P450 (CYP) enzymes—especially CYP3A4, CYP2C9, CYP2C19 and CYP1A2—which can increase blood levels ...

Jan 10, 2026
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Does ivermectin interact pharmacologically with opioids or benzodiazepines to increase respiratory depression?

Ivermectin has biologic actions on GABAergic and benzodiazepine receptor systems in experimental models and public health agencies warn it can potentiate other central nervous system (CNS) depressants...

Jan 19, 2026

How should dosing be adjusted for ivermectin when a patient is on multiple prescription drugs?

When patients take multiple prescription drugs, ivermectin dosing is not a one-size-fits-all calculation but a weight-based starting point (typically ~150–200 mcg/kg) that must be reconsidered in ligh...

Jan 6, 2026

What do user reviews say about Brain Defender side effects?

User reviews and coverage paint a consistent picture: most consumers report only mild, short-lived side effects such as digestive upset, headaches, nausea, restlessness or mood changes, while some rev...

Jan 5, 2026

Does Lipovive require dose adjustment for kidney or liver impairment?

The authoritative prescribing information consulted (for LIVALO, pitavastatin) makes clear renal guidance: no dose change for mild renal impairment but a reduced starting dose (1 mg once daily) is rec...